A health-related quality-of-life instrument for symptomatic patients with endometriosis: A validation study

H H Colwell, Colwell HH, Hilary H. Colwell, Susan D. Mathias, Mathias SD, S D Mathias, D J Pasta, David J. Pasta, James M. Henning, J M Henning, Henning JM, John F. Steege, J F Steege, Steege JF
American journal of obstetrics and gynecology · 1998 · vol. 179(1) , pp. 47–55 · doi:10.1016/s0002-9378(98)70250-9 · PMID:9704764 · W2045022532
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This study validated a new health-related quality-of-life instrument designed specifically for patients experiencing symptoms of endometriosis.

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Abstract

ObjectiveThis study was designed to evaluate the reliability, validity, and responsiveness of a newly developed, health-related quality-of-life measure.Study designA total of 137 women (122 from a Phase III clinical trial and 15 from a private practice setting) with endometriosis completed the questionnaire several times.ResultsReproducibility and internal-consistency reliability were acceptable with intraclass correlation coefficients ranging from 0.94 to 1.00 and Cronbach's alpha coefficients ranging from 0.84 to 0.97. Construct validity was demonstrated on the basis of correlations between items and scales. Health-related quality of life varied in a consistent manner according to clinician-rated measures of pelvic pain and dysmenorrhea and patient-reported levels of endometriosis pain, but no relationship emerged according to the revised American Fertility Society classification. In general, the questionnaire was moderately to highly responsive to change.ConclusionThis is the first comprehensive health-related quality-of-life questionnaire available for use with endometriosis patients that has demonstrated reliability, validity, and responsiveness.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Leuprolide Quality of Life Adolescent Adult Demography Endometriosis Endometriosis Female Humans Leuprolide Pain Measurement Pain Measurement Psychometrics Reproducibility of Results Surveys and Questionnaires

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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