Pathophysiology, diagnosis and treatment of endometriosis
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⤵ 25 in-corpus citations
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This review discusses endometriosis, a condition characterized by pain and infertility with a tendency towards progression, focusing on its pathophysiology, diagnosis, and individually adjusted surgical and medical treatments.
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Abstract
Endometriosis is generally a benign condition. However, there is a tendency towards progression and in part deep infiltrating processes occur, which can lead to obstruction and even silent loss of organ function such as kidney failure. Hereditary, genetic and immunological peculiarities have been found. Important are symptoms such as pain and infertility, which burden the life of the women involved. In spite of extensive research in the past the pathogenesis and epidemiology of the disease are not definitely clarified as yet. The estimated prevalence of endometriosis ranges between 10% and even more than 50% depending on the underlying problems of the women studied. Besides the main location of the disease within the pelvis also extra pelvic locations have been found (lung, lymph nodes, scars). The diagnosis should be established by histological verification. The main therapeutic modalities consist of surgery and medical treatment or combinations, which need to be individually adjusted, because of the high risk of recurrence and progression of the disease. The aim should be early detection and treatment as complete as possible, since symptom relief, resolution or prevention of infertility and decrease of recurrences are at their best under these circumstances.
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Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]
Cited by (25)
- The clinical importance of Magnetic Resonance Imaging with Diffusion weighted images in diagnosis and treatment planning of endometriosis. 2021
- Environmental Factors and Endometriosis 2021
- Endometriosis diagnosis and medical treatment: Present and future 2021
- Fertility outcomes of deep infiltrating endometriosis with fertility desire—a meta analysis 2020
- Fertility outcomes of deep infiltrating endometriosis with fertility desire——a meta analysis 2020
- MR findings for differentiating decidualized endometriomas from seromucinous borderline tumors of the ovary 2020
- Comparison of preoperative and postoperative sexual function in patients with deeply infiltrating endometriosis with and without bowel resection 2019
- Novel Drug Targets with Traditional Herbal Medicines for Overcoming Endometriosis 2018
- Familial deep endometriosis: A rare monogenic disease? 2017
- Transvaginal ultrasound vs magnetic resonance imaging for diagnosing deep infiltrating endometriosis: systematic review and meta-analysis 2017
- Epidemiology of Endometriosis in France: A Large, Nation-Wide Study Based on Hospital Discharge Data 2016
- Development of peritoneal endometriosis: Characterisation of immune environment in peritoneal endometriotic lesions 2015
- Increased 18F-FDG uptake of widespread endometriosis mimicking ovarian malignancy 2014
- Неконтрацептивные положительные эффекты комбинированных оральных контрацептивов 2013
- Accuracy of transvaginal sonography and contrast-enhanced magnetic resonance-colonography for the presurgical staging of deep infiltrating endometriosis 2012
- Novel therapies targeting endometriosis 2011
- Diagnosis of colorectal endometriosis: contribution of contrast enhanced MR-colonography 2011
- "Wpyw preparatu RESAN na odpowied ź immunologiczn ą typu Th 1 i Th2 w endometriozie- badanie do świadczalne na modelu zwierz ęcym" 2011
- Visceral hypersensitivity in endometriosis: a new target for treatment? 2011
- Hormonal contraceptives and endometriosis/adenomyosis 2010
- Endometriosis of the diaphragm: four cases treated with a combination of laparoscopy and thoracoscopy 2009
- Dienogest and the breast 2009
- Efficiency of MR imaging to orientate surgical treatment of posterior deep pelvic endometriosis 2008
- Zur Bedeutung der Endometriose in der Reproduktionsmedizin 2007
- High-dose pilot study with the novel progestogen dienogestin patients with endometriosis 2006
Source provenance
- europepmc
- last seen: 2026-10-16T06:09:50.462052+00:00
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-10-08T21:02:47.667321+00:00
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