Novel Diagnostic Markers for Endometriosis

Żaneta Kimber-Trojnar, Aleksandra Pilszyk, Pilszyk A, Niebrzydowska M, Magdalena Niebrzydowska-Tatus, Pilszyk Z, Zuzanna Pilszyk, Monika Ruszała, Ruszała M, Leszczyńska-Gorzelak B, Bożena Leszczyńska‐Gorzelak
2021 · doi:10.20944/preprints202103.0544.v1 · W3138414812
Review preprint OA: green CC0 ⤵ 1 in-corpus citation
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⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-09 ⓘ

This study explores potential non-invasive biomarkers, including glycoproteins, growth factors, and immune markers, to improve and expedite endometriosis diagnosis, which currently relies on invasive methods and has a lengthy diagnostic timeline.

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Abstract

Endometriosis is a disease that affects women of reproductive age and has a significant impact on their well-being. The main symptoms are dysmenorrhea, chronic pelvic pain and infertility. The diagnostic process in many cases is very long and can take up to 8-12 years. Laparoscopy, which is an invasive method, is still necessary to confirm final identification. Therefore, the development of diagnostic markers seems to be crucial for the diagnosis and proper treatment of women affected by endometriosis as soon as possible. Still the most frequently studied and used marker is Cancer Antigen 125 (CA-125). Other glycoproteins, growth factors and immune markers seem to play an important role. However, the search for the ideal endometriosis marker is still ongoing. Developing researches on endometriosis pathogenesis help to identify potential biomarkers or sets of biomarkers in order to improve and speed up the diagnostic process in a non-invasive way.

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Condition tags

endometriosischronic_pelvic_paindysmenorrheainfertility

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

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