Short Communication: In Vitro Fertilization in Patients with Ovarian Endometrioma

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Laparoscopic cystectomy for recurrent ovarian endometrioma during IVF showed improved oocyte fertilization and embryo cleavage rates in patients without endometrioma compared to those with recurrent endometrioma.

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Abstract

PurposeTo assess the influence of ovarian endometrioma during IVF.MethodsPatients were submitted to cystectomy by the laparoscopic route for exeresis of ovarian endometrioma. Group I (n = 28) consisted of patients without ovarian endometrioma and group II (n = 14) consisted of patients with recurrence of ovarian endometrioma during IVF.ResultsFertilization and cleavage rates were higher in group I and the pregnancy rate per transfer was similar in the two groups.ConclusionsThe presence of endometrioma during IVF causes a worsening of oocyte fertilization and embryo cleavage but does not affect the pregnancy rate per transfer.
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Abstract

Purpose: To assess the influence of ovarian endometrioma during IVF.

Methods

Patients were submitted to cystectomy by the laparoscopic route for exeresis of ovarian endometrioma. Group I (n = 28) consisted of patients without ovarian endometrioma and group II (n = 14) consisted of patients with recurrence of ovarian endometrioma during IVF.

Results

Fertilization and cleavage rates were higher in group I and the pregnancy rate per transfer was similar in the two groups.

Conclusions

The presence of endometrioma during IVF causes a worsening of oocyte fertilization and embryo cleavage but does not affect the pregnancy rate per transfer.

References

Arici A, Oral E, Bukulmez O, Dulela A, Olive D, Jones EE: The effect of endometriosis on implantation: Results from the Yale University in vitro fertilization and embryo transfer program. Fertil Steril 1996;65:603-607 Cahill DJ, Wardle PG, Maile LA, Harlow CR, Hull MG: Ovarian dysfunction in endometriosis-associated and un-explained infertility.J Assist Reprod Genet 1997;14:554-557 Yanushpolsky EH, Best CL, Jackson KV, Clarke RL, Hornstein MD: Effects of endometriomas on oocyte quality, embryo quality, and pregnancy rates in in vitro fertilization cycles: A prospective case-controlled study. J Assist Reprod Genet 1998;15:193-197 Pal L, Shifren JL, Isaackson KB, Chang Y, Leykin L, Toth TL: Impact of varying stages of endometriosis on the outcome of in vitro fertilization-embryo transfer. J Assist Reprod Genet 1998;11:27-31 Hemmings R, Bissonnette F, Bouzayen R: Results of laparoscopic treatments of ovarian endometriomas: Laparoscopic ovarian fenestration and coagulation. Fertil Steril 1998;70:527-529 Hsin-Yi Ho, Lee RKK, Hwu YM, Lin MH, Su JT, Tsai YC: Poor response of ovaries with endometrioma previously treated with cystectomy to control ovarian hyperstimulation. J Assist Re-prod Genet 2002;19:507-511 Donnez J, Wyns C, Nisolle M: Does ovarian surgery for en-dometriomas impair the ovarian response to gonadotropin? Fertil Steril 2001;76:662-665 Khamsi F, Yavas Y, Lacanna IC, Roberge S, Endman M, Wong JC: Exposure of human oocytes to endometrioma fluid does not alter fertilization or early embryo development. J Assist Reprod Genet 2001;18:106-109 Tinkanen H, Kujansuu E: In vitro fertilization in patients with ovarian endometriomas. Acta Obstet Gynecol Scand 2000;79:119-122 Ayers JWT, Birenbaum DL, Jiaram Menon KM: Luteal phase dysfunction in endometriosis: Elevated progesterone levels in peripheral and ovarian veins during the follicular phase. Fertil Steril 1987;47:925-929 Pellicer A, Oliveira N, Ruiz A, Remohi J, Simon C: Exploring the mechanism(s) of endometriosis-related infertility: An analysis of embryo development and implantation in assisted reproduction. Hum Reprod 1995;10:91-97 Lucena E, Cubillos J: Immune abnormalities in endometrio-sis compromising fertility in IVF-ET patients. J Reprod Med 1999;44:458-464 Marconi G, Vilela M, Quintana R, Sueldo C: Laparoscopic ovarian cystectomy of endometriomas does not affect the ovarian response to gonadotropin stimulation. Fertil Steril 2002:78:876-878 Author information Authors and Affiliations Rights and permissions About this article Cite this article dos Reis, R.M., Corrêa, I.L.A., De Ângelo, A.G. et al. Short Communication: In Vitro Fertilization in Patients with Ovarian Endometrioma. J Assist Reprod Genet 21, 311–314 (2004). https://doi.org/10.1023/B:JARG.0000043706.57616.74 Issue date: DOI: https://doi.org/10.1023/B:JARG.0000043706.57616.74

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Condition tags

endometriosisendometrioma

MeSH descriptors

Endometriosis Fertilization in Vitro Ovarian Diseases Pregnancy Rate Adult Cystectomy Endometriosis Endometriosis Female Humans Laparoscopy Ovarian Diseases Ovarian Diseases Pregnancy

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