Pathophysiologic features of “thin” endometrium

Ichiro Miwa, Hiroshi Tamura, Akihisa Takasaki, Yoshiaki Yamagata, Katsunori Shimamura, Norihiro Sugino
In: Fertility and Sterility · 2008 · vol. 91(4) , pp. 998–1004 · doi:10.1016/j.fertnstert.2008.01.029 · PMID:18328483 · W2022950254
article OA: closed CC0 ⤵ 22 in-corpus citations
View on OpenAlex View on PubMed View at publisher
⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

This paper investigates the underlying causes and characteristics of the "thin" endometrium, a condition affecting female fertility.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

ObjectiveTo characterize pathophysiologic features of a "thin" endometrium.DesignA prospective observational study.SettingUniversity Hospital and City General Hospital.Patient(s)Patients with normal-thickness endometrium (Normal-Em group: endometrial thickness >or=8 mm; n = 57) and thin endometrium (Thin-Em group: endometrial thickness <8 mm; n = 17).Main outcome measure(s)Blood flow impedance of the uterine radial artery (RA) was assessed as resistance index (RI) by transvaginal color-pulsed Doppler ultrasonography. The area of glandular epithelium, the number of blood vessels, and vascular endothelial growth factor (VEGF) expression were examined in the midluteal-phase endometrium.Result(s)The RA-RI in the Thin-Em group was significantly higher than in the Normal-Em group throughout the menstrual cycle. Endometrial thickness was significantly correlated with RA-RI. Growth of glandular epithelium, the number of blood vessels, and VEGF expression were significantly lower in the Thin-Em group than in the Normal-Em group.Conclusion(s)A "thin" endometrium was characterized by high blood flow impedance of RA, poor epithelial growth, decreased VEGF expression, and poor vascular development.

My notes (saved in your browser only)

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (47)

Cited by (22)

Source provenance

openalex
last seen: 2026-05-14T06:02:11.780192+00:00
unpaywall
last seen: 2026-06-05T02:00:03.366016+00:00
License: CC0 · commercial use OK