Evaluation of the ocular surface by impression cytology in patients with endometriosis

Objective The aim of this study was to investigate the effect of endometriosis on the ocular surface.

A total of 50 patients were included in the study and divided into two groups. Group 1 consisted of 25 patients with endometriosis. Group 2 had 25 control patients. All patients underwent complete ophthalmic examination, and the right eyes were included in the study. To evaluate the ocular surface, both groups were tested with the following: the Schirmer I test, tear breakup time (TBUT), the conjunctival impression cytology (CIC), and the Ocular Surface Disease Index (OSDI). The results were subsequently compared.

The average Schirmer I test results were 8.40 ± 2.74 mm in group 1 and were significantly lower in patients with endometriosis (P < 0.001). The average TBUT test results were 9.04 ± 3.61 s in group 1 and were significantly lower in patients with endometriosis (P < 0.001). The average OSDI results were 24.04 ± 9.29 in group 1 and were significantly higher in patients with endometriosis (P < 0.001). The average CIC results were 1.76 ± 0.88 in group 1 and were significantly higher in patients with endometriosis (P < 0.001).

Ocular surface changes, including squamous metaplasia, may be observed in the conjunctiva of patients with endometriosis. Access this article We’re sorry, something doesn't seem to be working properly. Please try refreshing the page. If that doesn't work, please contact support so we can address the problem. Similar content being viewed by others

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Ethical approval “All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee (ethical committee of Balıkesir University Medical Faculty (registration number: 2019/60) and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.” Informed consent “Informed consent was obtained from all individual participants included in the study.” Additional information Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Rights and permissions About this article Cite this article Turan, M., Turan, G. & Usta, A. Evaluation of the ocular surface by impression cytology in patients with endometriosis. Graefes Arch Clin Exp Ophthalmol 258, 931–937 (2020). https://doi.org/10.1007/s00417-019-04591-w Received: Revised: Accepted: Published: Version of record: Issue date: DOI: https://doi.org/10.1007/s00417-019-04591-w