Pharmacological treatment of endometriosis: update from recent clinical trials

Simone Ferrero, Valentino Remorgida, Pier Luigi Venturini
In: Clinical Investigation · 2011 · vol. 1(1) , pp. 109–117 · doi:10.4155/cli.10.4 · W2053768378
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This review discusses pharmacological treatments for endometriosis-related pain, including updates on GnRH analogs, aromatase inhibitors, and recent advances for specific disease manifestations.

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Abstract

Endometriosis is a chronic disease that causes pain and infertility. Combined oral contraceptives and progestins are commonly used for the treatment of endometriosis because they reduce the severity of pain symptoms in 60–70% of patients and are well tolerated. Gonadotropin-releasing hormone analogs and danazol may be administered to selected patients but their long-term use is limited owing to the high frequency of severe adverse effects. Aromatase inhibitors should be administered only to women who fail to improve after surgery and conventional hormonal therapy because they are not well tolerated. This article discusses the medical therapies available for the treatment of endometriosis-related pain symptoms; in addition, detailed information on the recent advances in the treatment of rectovaginal endometriosis, ovarian endometriomas and bowel endometriosis is presented.

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Condition tags

endometriosisbowel_endometriosisinfertility

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (76)

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