Pathogenesis of endometriosis
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⤵ 18 in-corpus citations
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This review discusses the current understanding of endometriosis pathogenesis, including genetic, epigenetic, and immunological factors.
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Abstract
Many theories have been proffered to explain the histogenesis of endometriosis (Robboy et al., 2009). Generally, they divide into those that favour transplantation of endometrial fragments to ectopic sites, metaplasia of the multipotential celomic peritoneum and induction of undifferentiated mesenchyme in ectopic sites to form endometriotic tissues after exposure to substances released from shed endometrium.
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References (12)
- Ectopic endometrium in human foetuses is a common event and sustains the theory of müllerianosis in the pathogenesis of endometriosis, a disease that predisposes to cancer via openalex
- Endometriosis in a Patient with Rokitansky-Kuster-Hauser Syndrome via openalex
- Endometriosis: Increased prevalence and recurrence of retrograde menstruation in baboons with spontaneous endometriosis via openalex
- Nonhuman Primate Models for Translational Research in Endometriosis via openalex
- PATHOGENESIS OF ENDOMETRIOSIS via openalex
- The Secondary Müllerian System Revisited via openalex
- W2038221637 via openalex
- W2158721954 via openalex
- W2019379578 via openalex
- W2332638219 via openalex
- W6808209322 via openalex
- W6842164832 via openalex
Cited by (18)
- The Role of Adenogenesis Factors in the Pathogenesis of Endometriosis 2025
- Gonadotropin-releasing hormone analogues for endometriosis 2023
- Combined histological and DNA methylome profiling approaches may provide insights into the pathophysiology of ovarian endometriomas 2023
- New Insights in Pathogenesis of Endometriosis 2022
- Peculiarities of the clinical course and pathomorphological picture of ovarian endometriosis and adenomyosis in reproductive aged women 2022
- GENITAL ENDOMETRIOSIS ASSOCIATED WITH INFERTILITY 2022
- Endometriosis-associated ovarian cancer: What have we learned so far? 2019
- Effects of clarithromycin on inflammatory markers and clinical manifestations in postsurgical follow-up of patients with endometriosis: a double-blinded randomized placebo-controlled clinical trial 2019
- Influence of genital endometriosis and concomitant diseases on infertility under the data of the retrospective analysis of case histories 2019
- High expression of ZEB1 in endometriosis and its role in 17β-estradiol-induced epithelial-mesenchymal transition. 2018
- Lipoxin A4 Suppresses Estrogen-Induced Epithelial-Mesenchymal Transition via ALXR-Dependent Manner in Endometriosis 2017
- Endometriosis en el ciego de una mujer posmenopáusica. Reporte del caso 2017
- The codon 72 polymorphism of the TP53 gene and endometriosis risk: a meta-analysis 2015
- Lipoxin <scp>A</scp><sub>4</sub> suppresses the development of endometriosis in an <scp>ALX</scp> receptor‐dependent manner via the p38 <scp>MAPK</scp> pathway 2014
- Endometriosis: A Disease That Remains Enigmatic 2013
- Extracts of <i>Salvia miltiorrhiza</i> bunge on the cytokines of rat endometriosis models 2012
- The role of prostaglandin E <sub>2</sub> in endometriosis 2011
- Indications and Limits to Endourologic Procedures for Endometriosis of the Urinary Tract 2010
Source provenance
- europepmc
- last seen: 2026-10-03T06:16:46.921020+00:00
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-05-13T22:17:07.008521+00:00
- unpaywall
- last seen: 2026-10-03T06:31:36.481334+00:00
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