The impact on ovarian reserve of haemostasis by bipolar coagulation versus suture following surgical stripping of ovarian endometrioma: a meta-analysis

Wenjing Ding, Ding W, Wenjiang Ding, Li M, Ming Li, Teng Y, Yincheng Teng
Reproductive BioMedicine Online · 2015 · vol. 30(6) , pp. 635–642 · doi:10.1016/j.rbmo.2015.02.012 · PMID:25913247 · W2045334571
Systematic review / meta-analysis OA: closed CC0 ⤵ 29 in-corpus citations
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This meta-analysis compared bipolar coagulation and suture methods for ovarian endometrioma stripping hemostasis, assessing their impact on ovarian reserve.

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Abstract

Concern is increasing that the use of bipolar coagulation or suturing to obtain haemostasis after surgical stripping of ovarian endometrioma could affect ovarian reserve. To compare the ovarian damage associated with the use of bipolar coagulation with ovarian suture as determined by anti-Müllerian hormone (AMH), FSH and antral follicle count, 21 studies were identified. Pooled analysis of 312 patients showed the average serum level of AMH was lower in the coagulation group than in the suture group (3-month follow-up: weighted mean difference (WMD) -0.75 ng/ml, 95% confidence interval (CI) -1.82 to 0.31; 6 months: WMD -1.45 ng/ml, 95% CI -2.43 to -0.47; 12 months: WMD -1.01 ng/ml; 95% CI -1.85 to -0.17), although heterogeneity was high. The weighted overall average levels of FSH between the two groups were not statistically significantly different 3 months after surgery (WMD 0.37 mIU/ml; 95% CI -1.56 to 1.30). The mean antral follicle count in the coagulation group was significantly less than in the suture group at 3 months' follow-up (WMD -2.53, with 95% CI -4.94 to -0.12). This study showed bipolar coagulation did more harm to the ovarian reserve than the suture haemostasis during excision of ovarian cyst as shown by a significant postoperative reduction in AMH.

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Condition tags

endometriosisendometrioma

MeSH descriptors

Endometriosis Hemostasis Hemostasis Ovarian Neoplasms Sutures Sutures Anti-Mullerian Hormone Anti-Mullerian Hormone Anti-Mullerian Hormone Endometriosis Endometriosis Endometriosis Endometriosis Female Female Humans Humans Ovarian Neoplasms Ovarian Neoplasms Ovarian Neoplasms

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (37)

Cited by (31)

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