Potential damage to ovarian reserve from laparoscopic electrocoagulation in endometriomas and benign ovarian cysts: a systematic review and meta-analysis
meta-analysis
OA: green
CC0
⤵ 4 in-corpus citations
AI-generated summary
Nonthermal hemostatic methods better preserve ovarian reserve than bipolar electrocoagulation for laparoscopic endometrioma removal, but not for benign ovarian cysts.
One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works
Abstract
PURPOSE: Laparoscopic cystectomy for ovarian endometriomas and benign ovarian cysts is often conducted through hemostatic methods, with bipolar electrocoagulation as a common approach. This study evaluated the impact of electrocoagulation, primarily through bipolar energy, versus nonthermal hemostatic methods on ovarian reserve in patients undergoing laparoscopic cystectomy for ovarian endometriomas and benign ovarian cysts.
METHODS: A systematic review with meta-analysis was conducted by searching the Cochrane Library, PubMed, EMBASE, and Web of Science databases. Randomized controlled trials (RCTs) comparing the impact of nonthermal hemostatic methods and electrocoagulation on the ovarian reserve during laparoscopic cystectomy were included. The Cochrane Risk of Bias Tool for Randomized Controlled Trials (ROB 2.0) was utilized to assess the quality of the included studies. The meta-analysis included 13 RCTs involving 1043 patients. Postoperative serum anti-Müllerian hormone (AMH) levels and antral follicle counts (AFCs) were analyzed using Review Manager ver. 5.4.
RESULTS: Compared with the bipolar group, patients with endometriomas in the nonthermal hemostatic group exhibited significantly higher postoperative AMH levels at 1, 3, 6, and 12 months. Conversely, no significant differences in AMH levels were observed in patients with benign ovarian cysts. Similarly, AFCs showed no significant differences, except for lower postoperative AFCs in patients with endometrioma in the electrocoagulation group.
CONCLUSION: Nonthermal hemostatic methods are associated with more effective preservation of the ovarian reserve compared with bipolar electrocoagulation in laparoscopic cystectomy for ovarian endometriomas. However, no significant impact of bipolar electrocoagulation on the ovarian reserve was observed in patients with benign ovarian cysts.
TRIAL REGISTRATION: Registered in PROSPERO on April 10, 2023; ID # CRD42023413158.
My notes (saved in your browser only)
Ask this paper
Answers must be backed by verbatim quotes from this paper's full text. Hallucinated quotes are dropped automatically; if no verbatim passage answers the question, we say so. How this works
Condition tags
MeSH descriptors
Citation neighborhood
Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.
References (40)
- Additional benefit of hemostatic sealant in preservation of ovarian reserve during laparoscopic ovarian cystectomy: a multi-center, randomized controlled trial via openalex
- A randomized controlled trial of ovarian reserve preservation and hemostasis during ovarian cystectomy via openalex
- Comparing ovarian reserve after laparoscopic excision of endometriotic cysts and hemostasis achieved either by bipolar coagulation or suturing: a randomized clinical trial via openalex
- Effect of surgery on ovarian reserve in women with endometriomas, endometriosis and controls via openalex
- Endometrioma and ovarian reserve: effects of endometriomata per se and its surgical treatment on the ovarian reserve. via openalex
- Impact of hemostatic methods on ovarian reserve and fertility in laparoscopic ovarian cystectomy via openalex
- Impact of the hemostatic approach after laparoscopic endometrioma excision on ovarian reserve: Systematic review and network meta-analysis of randomized controlled trials via openalex
- Impact of unilateral versus bilateral ovarian endometriotic cystectomy on ovarian reserve: a systematic review and meta-analysis via openalex
- Laparoscopic excision of ovarian cysts: is the stripping technique a tissue-sparing procedure? via openalex
- Long-Term Follow-Up Of Anti-Mullerian Hormone Levels After Laparoscopic Endometrioma Cystectomy via openalex
- One-year follow-up of serum antimüllerian hormone levels in patients with cystectomy: are different sequential changes due to different mechanisms causing damage to the ovarian reserve? via openalex
- Ovarian function following use of various hemostatic techniques during treatment for unilateral endometrioma: A randomized controlled trial via openalex
- Ovarian reserve and recurrence 1 year post-operatively after using haemostatic sealant and bipolar diathermy for haemostasis during laparoscopic ovarian cystectomy via openalex
- Ovarian reserve evaluation after laparoscopic cyst enucleation, depending on applied haemostasis technique and with particular consideration of endometrial cysts via openalex
- Pathophysiology proposed as the basis for modern management of the ovarian endometrioma via openalex
- Serum anti-Müllerian hormone level is a useful marker for evaluating the impact of laparoscopic cystectomy on ovarian reserve via openalex
- Serum anti-Müllerian hormone levels decrease after endometriosis surgery via openalex
- Systematic review and meta‐analysis of the effect of bipolar electrocoagulation during laparoscopic ovarian endometrioma stripping on ovarian reserve via openalex
- The Impact of Endometriosis and Its Treatment on Ovarian Reserve via openalex
- The Impact of Excision of Ovarian Endometrioma on Ovarian Reserve: A Systematic Review and Meta-Analysis via openalex
- The impact on ovarian reserve of haemostasis by bipolar coagulation versus suture following surgical stripping of ovarian endometrioma: a meta-analysis via openalex
- Usefulness of hemostatic sealants for minimizing ovarian damage during laparoscopic cystectomy for endometriosis via openalex
- Which Should Be the Preferred Technique During Laparoscopic Ovarian Cystectomy: Hemostatic Sutures or Bipolar Electrocoagulation? A Randomized Controlled Prospective Study of Long-Term Ovarian Reserve via openalex
- doi:10.3802/jgo.2017.28.e37 via openalex
- doi:10.1007/s00404-012-2704-9 via openalex
- doi:10.1016/j.fertnstert.2013.10.019 via openalex
- doi:10.1016/j.fertnstert.2009.02.022 via openalex
- doi:10.5152/jtgga.2012.28 via openalex
- doi:10.1016/j.jmig.2010.03.021 via openalex
- W31130373 via openalex
- doi:10.1016/j.ejogrb.2010.02.029 via openalex
- doi:10.1016/j.ejogrb.2014.10.012 via openalex
- doi:10.1093/humupd/dmu020 via openalex
- doi:10.1093/humrep/den301 via openalex
- doi:10.1016/j.fertnstert.2014.12.093 via openalex
- doi:10.1016/j.tjog.2015.08.026 via openalex
- W6601282674 via openalex
- doi:10.1093/humupd/dmp036 via openalex
- doi:10.1016/j.jviscsurg.2018.04.001 via openalex
- doi:10.1186/s13048-019-0542-0 via openalex
Cited by (4)
- Autologous platelet-rich fibrin glue in surgery of endometrioid ovarian cysts: a strategy for preserving ovarian reserve 2026
- Optimal Laparoscopic Surgical Technique for Preserving Fertility and Ovarian Reserve in Patients with Endometrioma: A Systematic Review and Bayesian Network Meta-Analysis of Randomized Controlled Trials 2026
- Evidence on Serum Anti-Müllerian Hormone Levels and Endometriosis Surgery 2025
- Endometrioma and Infertility 2025
Source provenance
- europepmc
- last seen: 2026-06-04T01:30:01.192114+00:00
- openalex
- last seen: 2026-05-11T05:41:49.878000+00:00
- pmc
- last seen: 2026-05-13T20:22:03.195721+00:00
- pubmed
- last seen: 2026-06-01T00:32:25.446589+00:00
License: CC0
· commercial use OK