Ovarian function following use of various hemostatic techniques during treatment for unilateral endometrioma: A randomized controlled trial

Raquel Silveira da Cunha Araujo, Raquel Silveira da Cunha Araújo, Sabina Bastos Maia, Clara Micalli Ferruzzi Baracat, Clarissa Queiroz Bezerra de Araujo Fernandes, Helizabet Salomão Abdalla Ayroza Ribeiro, Paulo Ayroza Ribeiro, Paulo Augusto Ayroza Galvão Ribeiro
International Journal of Gynecology & Obstetrics · 2021 · vol. 157(3) , pp. 549–556 · doi:10.1002/ijgo.13912 · PMID:34478564 · W3197054957
article OA: closed CC0 ⤵ 10 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

This RCT compared bipolar energy, hemostatic sealants, and sutures for ovarian function after endometrioma cystectomy, finding no significant differences in AMH levels between the techniques.

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Abstract

OBJECTIVE: To compare the effect of hemostatic techniques (bipolar energy versus hemostatic sealants versus suture) on the ovarian reserve of patients submitted to laparoscopic cystectomy for the surgical excision of unilateral endometrioma. METHODS: A randomized controlled trial conducted in a teaching hospital included 84 patients with unilateral endometrioma. The patients underwent laparoscopic stripping for excision of the unilateral endometrioma between March 2018 and February 2020. Three different hemostatic techniques-bipolar energy (Group 1), hemostatic sealants (Group 2), and suture (Group 3)-were compared. Anti-Müllerian hormone (AMH) levels were measured before, and 1 and 6 months after surgery to determine changes in ovarian function. RESULTS: Following surgery, AMH levels decreased in all the groups; however, this decrease was not statistically significant. Comparison between groups showed no statistically significant differences in AMH levels between the three hemostatic techniques used. Six months after surgery, median AMH levels were: 1.65 ng/mL (interquartile range [IQR] 0.62-2.08 ng/mL) in Group 1, 1.87 ng/mL (IQR 1.27-2.97 ng/mL) in Group 2, and 1.53 ng/mL (IQR 1.18-2.44 ng/mL) in Group 3. CONCLUSION: The present study suggests that there is no difference between the different hemostatic techniques used in laparoscopic cystectomy for the treatment of unilateral endometriomas. Registered at ClinicalTrials.gov: NCT03430609. https://clinicaltrials.gov/ct2/show/NCT03430609.

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Condition tags

mesh:D004715endometrioma

MeSH descriptors

Endometriosis Endometriosis Hemostatics Hemostatics Laparoscopy Laparoscopy Ovarian Cysts Ovarian Cysts Ovarian Reserve Anti-Mullerian Hormone Female Hemostatic Techniques Humans

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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Cited by (10)

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