Ovarian function following use of various hemostatic techniques during treatment for unilateral endometrioma: A randomized controlled trial

Raquel Silveira da Cunha Araujo, Araujo RSDC, Raquel Silveira da Cunha Araújo, Sabina Bastos Maia, Maia SB, Clara Micalli Ferruzzi Baracat, Baracat CMF, Fernandes CQBA, Clarissa Queiroz Bezerra de Araujo Fernandes, Helizabet Salomão Abdalla Ayroza Ribeiro, Ribeiro HSAA, Paulo Augusto Ayroza Galvão Ribeiro, Ribeiro PAAG, Paulo Ayroza Ribeiro
International Journal of Gynecology & Obstetrics · 2021 · vol. 157(3) , pp. 549–556 · doi:10.1002/ijgo.13912 · PMID:34478564 · W3197054957
RCT OA: closed CC0 ⤵ 10 in-corpus citations
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This RCT compared bipolar energy, hemostatic sealants, and sutures for ovarian function after endometrioma cystectomy, finding no significant differences in AMH levels between the techniques.

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Abstract

OBJECTIVE: To compare the effect of hemostatic techniques (bipolar energy versus hemostatic sealants versus suture) on the ovarian reserve of patients submitted to laparoscopic cystectomy for the surgical excision of unilateral endometrioma. METHODS: A randomized controlled trial conducted in a teaching hospital included 84 patients with unilateral endometrioma. The patients underwent laparoscopic stripping for excision of the unilateral endometrioma between March 2018 and February 2020. Three different hemostatic techniques-bipolar energy (Group 1), hemostatic sealants (Group 2), and suture (Group 3)-were compared. Anti-Müllerian hormone (AMH) levels were measured before, and 1 and 6 months after surgery to determine changes in ovarian function. RESULTS: Following surgery, AMH levels decreased in all the groups; however, this decrease was not statistically significant. Comparison between groups showed no statistically significant differences in AMH levels between the three hemostatic techniques used. Six months after surgery, median AMH levels were: 1.65 ng/mL (interquartile range [IQR] 0.62-2.08 ng/mL) in Group 1, 1.87 ng/mL (IQR 1.27-2.97 ng/mL) in Group 2, and 1.53 ng/mL (IQR 1.18-2.44 ng/mL) in Group 3. CONCLUSION: The present study suggests that there is no difference between the different hemostatic techniques used in laparoscopic cystectomy for the treatment of unilateral endometriomas. Registered at ClinicalTrials.gov: NCT03430609. https://clinicaltrials.gov/ct2/show/NCT03430609.

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Condition tags

endometriosisendometrioma

MeSH descriptors

Endometriosis Endometriosis Endometriosis Hemostatics Hemostatics Hemostatics Laparoscopy Laparoscopy Laparoscopy Ovarian Cysts Ovarian Cysts Ovarian Cysts Ovarian Reserve Ovarian Reserve Anti-Mullerian Hormone Anti-Mullerian Hormone Female Female Hemostatic Techniques Hemostatic Techniques

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (27)

Cited by (10)

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