Randomized clinical trial of ovarian reserve capacity after laparoscopic stripping of ovarian endometriomas

Objective: To investigate the influence of different hemostasis approaches after laparoscopic stripping for endometriosis on ovarian reserve capacity.Methods: 100 ovarian endometriomas patients treated with elective laparoscopic cystectomy from January to December 2010 were prospectively enrolled,and were randomly divided into two groups with 50 patients in each.Ovarian hemostasis was obtained either by bipolar electrocoagulation in group A,or by suturing in group B.Ovarian antral follicles(AFC) was performed by ultrasound on the third day of the three postoperative menstrual cycles,while follicle stimulating hormone(FSH) was measured in the same day.They were followed up at the 2,4 and 6 menstrual cycle,and the outcomes were compared between the two groups.Results: The baselines characteristics of two groups were statistically similar.AFC was significantly fewer than that of the normal ovarian tissue.AFC in group A was significantly lower than that in group B at each time point,while FSH level was significantly higher than that in group A,and there were significant differences between the two groups(all P0.001).Conclusion: Ovarian endometriomas can reduce ovarian reserve.The AFC value suggests that the ovarian reserve is less reduced in sutured ovaries than in those electrocoagulated.Suturing as a method of hemostasis should be recommended as a better choice after stripping ovarian endometriomas.