Levels of prostaglandins F2α and E2 in human endometrium during the menstrual cycle
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This study measured prostaglandins F2α and E2 in human endometrium across the menstrual cycle to understand their dynamic changes.
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Abstract
A comparison between the prostaglandins found in proliferative and secretory endometrium in normal and tumor-bearing tissues is reported. The content of prostaglandins F-2alpha and E-2 is related to the three phases of the menstrual cycle and correlates with cyclic ovarian hormone variations. The menstrual phase is characterized by a high content of PGF-2alpha. High prostaglandin levels are found in tissues from patients with pathologic diseases such as adenocarcinoma of the endometrium when compared to normal tissues.
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References (6)
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Cited by (24)
- Gut feeling: understanding the endometriosis-digestive link to enhance patient care and symptom control 2025
- Interleukin-1 type I receptor messenger ribonucleic acid expression in human endometrium throughout the menstrual cycle 1993
- Eicosanoids production in endometriosis 1992
- Prostaglandins in Dysmenorrhoea and Endometriosis 1992
- Menorrhagia 1990
- Eicosanoids in primary dysmenorrhea, endometriosis and menstrual migraine 1989
- The measurement of phospholipase A2 activity in human myometrium: Physiological and pathological implications 1988
- The activity of calcium dependent and calcium independent phospholipase A2 in normal endometrium and in endometrium from women suffering from menorrhagia and polycystic ovary syndrome 1988
- PHOSPHOLIPASE C ACTIVITY IN HUMAN ENDOMETRIUM: ITS SIGNIFICANCE IN ENDOMETRIAL PATHOLOGY 1987
- Endometrial phospholipase A2 enzymes and their regulation by steroid hormones 1987
- Eicosanoids, menstruation and menstrual disorders 1987
- Glucocorticoids do not share with progesterone the potent inhibitory action on prostaglandin synthesis in human proliferative phase endometrium 1987
- Endometriosis 1986
- Leiomyomas release prostaglandins 1985
- Etiology of infertility in monkeys with endometriosis: Measurement of peritoneal fluid prostaglandins 1984
- Endometrial and Myometrial Prostaglandin Release during the Menstrual Cycle in Relation to Menstrual Blood Loss* 1984
- Prostaglandin secretion by human endometrium in vitro 1982
- PROSTAGLANDIN SYNTHESIS IN THE ENDOMETRIUM OF WOMEN WITH OVULAR DYSFUNCTIONAL UTERINE BLEEDING 1981
- Dysmenorrhoea and Prostaglandins 1981
- Prostaglandins in primary dysmenorrhea 1981
- EFFECT OF SALBUTAMOL ON THE NON‐PREGNANT HUMAN UTERUS IN VIVO 1981
- New concepts in dysmenorrhea 1978
- The effect of naproxen-sodium on the prostaglandin concentrations of the menstrual blood and uterine “jet-washings” in dysmenorrehic women 1978
- STUDIES IN THE INVOLVEMENT OF PROSTAGLANDINS IN UTERINE SYMPTOMATOLOGY AND PATHOLOGY 1976
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