Systematic review and Meta-analysis of efficacy and safety of dienogest in treatment of endometriosis
This meta-analysis of randomized controlled trials found dienogest to be effective and safe for endometriosis treatment, showing significant improvements in pain symptoms and quality of life.
One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works
Abstract
My notes (saved in your browser only)
Condition tags
Citation neighborhood (2-hop)
Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]
References (41)
- A dose-ranging study to determine the efficacy and safety of 1, 2, and 4mg of dienogest daily for endometriosis via openalex
- Clinical dynamics of Dienogest for the treatment of endometriosis: from bench to bedside via openalex
- Comparison of dienogest versus triptorelin acetate in premenopausal women with adenomyosis: a prospective clinical trial via openalex
- Consensus on current management of endometriosis via openalex
- Defining a minimal clinically important difference for endometriosis-associated pelvic pain measured on a visual analog scale: analyses of two placebo-controlled, randomized trials via openalex
- Dienogest for Treatment of Endometriosis in Chinese Women: A Placebo-Controlled, Randomized, Double-Blind Phase 3 Study via openalex
- Dienogest improves human leucocyte antigen-DR underexpression and reduces tumour necrosis factor-α production in peritoneal fluid cells from women with endometriosis via openalex
- Dienogest inhibits nerve growth factor expression induced by tumor necrosis factor-α or interleukin-1β via openalex
- Dienogest inhibits Toll-like receptor 4 expression induced by costimulation of lipopolysaccharide and high-mobility group box 1 in endometrial epithelial cells via openalex
- Dienogest in the treatment of endometriosis-associated pelvic pain: a 12-week, randomized, double-blind, placebo-controlled study via openalex
- Dienogest is as effective as intranasal buserelin acetate for the relief of pain symptoms associated with endometriosis--a randomized, double-blind, multicenter, controlled trial via openalex
- Dienogest reduces proliferation, NGF expression and nerve fiber density in human adenomyosis via openalex
- Dienogest Versus Leuprolide Acetate for Recurrent Pelvic Pain Following Laparoscopic Treatment of Endometriosis via openalex
- Effect of dienogest administration on angiogenesis and hemodynamics in a rat endometrial autograft model via openalex
- Effects of dienogest on surgically induced endometriosis in rats after repeated oral administration via openalex
- Effects of long-term treatment with Dienogest on the quality of life and sexual function of women affected by endometriosis-associated pelvic pain via openalex
- Effects of ranibizumab and zoledronic acid on endometriosis in a rat model via openalex
- Endometriosis via openalex
- Endometriosis: pathogenesis and treatment via openalex
- ESHRE guideline for the diagnosis and treatment of endometriosis via openalex
- Ethinylestradiol 20 μg/drospirenone 3 mg in a flexible extended regimen for the management of endometriosis-associated pelvic pain: a randomized controlled trial via openalex
- Evaluation of the efficacy and safety of dienogest in the treatment of painful symptoms in patients with adenomyosis: a randomized, double-blind, multicenter, placebo-controlled study via openalex
- Exploratory study of pre-surgical medications with dienogest or leuprorelin in laparoscopic cystectomy of endometrial cysts via openalex
- Hormone treatment of endometriosis: the estrogen threshold hypothesis via openalex
- Is dienogest the best medical treatment for ovarian endometriomas? Results of a multicentric case control study via openalex
- Optimizing gonadotropin-releasing hormone agonist therapy in women with endometriosis via openalex
- Ovulation-inhibiting effects of dienogest in a randomized, dose-controlled pharmacodynamic trial of healthy women via openalex
- Pathogenesis and pathophysiology of endometriosis via openalex
- Progesterone and progestational compounds attenuate tumor necrosis factor alpha-induced interleukin-8 production via nuclear factor kappa B inactivation in endometriotic stromal cells via openalex
- Quality of life and sexual function of women affected by endometriosis-associated pelvic pain when treated with dienogest via openalex
- Reduced pelvic pain in women with endometriosis: efficacy of long-term dienogest treatment via openalex
- Rethinking mechanisms, diagnosis and management of endometriosis via openalex
- The significant effect of endometriosis on physical, mental and social wellbeing: results from an international cross-sectional survey via openalex
- Treatment of endometriosis in different ethnic populations: a meta-analysis of two clinical trials via openalex
- Women's experiences of endometriosis: a systematic review and synthesis of qualitative research via openalex
- W2012076119 via openalex
- W2079421112 via openalex
- W2166050085 via openalex
- W2021687464 via openalex
- W2996101359 via openalex
- W2101417341 via openalex
Cited by (4)
- Evaluation of the efficacy and tolerability of 4 mg dienogest in women with adenomyosis and BMI >30 2025
- Innovations in the diagnosis and treatment of endometriosis: from the current advancements to a future outlook: A review 2025
- The Efficacy of Medical Treatment on Endometrioma: A Systematic Review and Meta-Analysis 2024
- Efficacy and Safety of Dienogest in the Management of Women with Endometriosis; Systematic Review and Meta-Analysis 2023
Source provenance
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00