A Rare Case of Pancreatic Endometrial Cyst and Review of the Literature

Yamamoto R, Ryuichi Yamamoto, Konagaya K, Kensuke Konagaya, Iijima H, Hirokazu Iijima, Kashiwagi H, Hiroyuki Kashiwagi, Hashimoto M, Masanori Hashimoto, Shindo A, Asumi Shindo, Yuki Sasaki, Sasaki Y, Yamamoto K, Kota Yamamoto, Nakagawa M, Masashi Nakagawa, Yuma Suno, Suno Y, Abe T, Toshiyuki Abe, Mutsuo Takaki, Takaki M, Suda K, Koichi Suda, Kazuomi Watanabe, Watanabe K
Internal medicine (Tokyo, Japan) · 2018 · vol. 58(8) , pp. 1097–1101 · doi:10.2169/internalmedicine.1702-18 · PMID:30568111 · PMC6522422 · W2905178171
review OA: gold CC0 ⤵ 11 in-corpus citations
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⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-07 ⓘ

This case report details a rare pancreatic endometrial cyst diagnosed in a young patient and reviews the limited literature on this challenging condition.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-07 · read from full text ⓘ

This paper reports a rare case of a pancreatic endometrial cyst in a 26-year-old patient who presented with left abdominal pain and was found to have a large cyst in the pancreatic body. Laboratory tests showed elevated white blood cell count and C-reactive protein, while tumor markers were normal; surgical management consisted of distal pancreatectomy with splenectomy, and histopathology confirmed pancreatic endometriotic cysts. The authors note that only 13 prior cases had been reported and emphasize that preoperative diagnosis is difficult, with many patients undergoing resection due to suspected neoplasms. This paper is centrally about endometriosis — specifically a pancreatic endometrial (endometriotic) cyst confirmed by histopathology and reviewed in the context of reported cases.

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Abstract

Pancreatic cysts include a variety of benign, premalignant, and malignant lesions. Endometrial cysts in the pancreas are extremely rare lesions that are difficult to diagnose before surgery. We report the case of a 26-year-old patient with a recent episode of left abdominal pain who presented with a large cyst in the pancreatic body. Laboratory results showed white blood cell and C-reactive protein elevation, whereas the patient's tumor marker levels were within the normal range. Distal pancreatectomy with splenectomy was performed. The final histopathological examination confirmed the presence of endometriotic cysts within the pancreas. Only 13 cases of endometriotic cysts of the pancreas have been previously reported. The preoperative diagnosis is challenging, and most patients undergo pancreatic resection because of suspected neoplasms. This case report reviews previous studies and discusses the clinicopathological features, pathogenesis, and appropriate treatment for pancreatic endometrial cysts.
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Keywords

pancreas, endometrial cyst 2019 Volume 58 Issue 8 Pages 1097-1101 Details

Abstract

Pancreatic cysts include a variety of benign, premalignant, and malignant lesions. Endometrial cysts in the pancreas are extremely rare lesions that are difficult to diagnose before surgery. We report the case of a 26-year-old patient with a recent episode of left abdominal pain who presented with a large cyst in the pancreatic body. Laboratory results showed white blood cell and C-reactive protein elevation, whereas the patient's tumor marker levels were within the normal range. Distal pancreatectomy with splenectomy was performed. The final histopathological examination confirmed the presence of endometriotic cysts within the pancreas. Only 13 cases of endometriotic cysts of the pancreas have been previously reported. The preoperative diagnosis is challenging, and most patients undergo pancreatic resection because of suspected neoplasms. This case report reviews previous studies and discusses the clinicopathological features, pathogenesis, and appropriate treatment for pancreatic endometrial cysts. © 2019 by The Japanese Society of Internal Medicine Favorites & Alerts Recently viewed articles Predecessor

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Condition tags

endometriosis

MeSH descriptors

Abdominal Pain Endometriosis Pancreatectomy Pancreatic Cyst Pancreatic Cyst Pancreatic Neoplasms Rare Diseases Abdominal Pain Adult Aged Endometriosis Female Humans Middle Aged Pancreatectomy Pancreatic Cyst Pancreatic Cyst Pancreatic Cyst Pancreatic Neoplasms Pancreatic Neoplasms

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References (17)

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