Pancreatic endometrioma : a rare differential diagnosis for a pseudocyst

Dana AlNuaimi, Yasir Akmal, Ahmad Alduaij, Ahmed Sherif, Shareefa Abdulghaffar, N. Cem Balci, Numan Cem Balci
BJR case reports · 2022 · vol. 9(1) , pp. 20220141 · doi:10.1259/bjrcr.20220141 · PMID:36873241 · PMC9976728 · W4311862084
article OA: gold CC0 ⤵ 1 in-corpus citation
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⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

This case report presents a rare instance of pancreatic endometriosis mistaken for a pseudocyst in a 31-year-old female, with definitive diagnosis achieved through histopathology after robotic resection.

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Abstract

Pancreatic endometriosis is extremely rare with only 14 cases reported in the medical literature and its diagnosis on radiological imaging poses a great challenge. We report a case of a 31-year-old female patient with recurrent admissions for pancreatitis of unknown aetiology and no relevant previous medical history. Sectional imaging showed a cystic lesion in the tail of the pancreas and the diagnosis of a post-pancreatitis pseudocyst or a less likely pre-malignant mucinous cystadenoma was considered. On post-robotic resection of the pancreatic cyst, the histopathology analysis was positive for endometrial stroma. Pancreatic endometriosis although rare should be considered as a differential diagnosis for cystic lesions especially in patients who are known to have pelvic endometriosis. Nevertheless, the gold standard for the definite diagnosis of pancreatic endometriosis remains histopathological.

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endometriosisendometrioma

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