The use of serial CA 125 concentrations to monitor endometriosis in infertile women
Observational
OA: closed
CC0
⤵ 15 in-corpus citations
AI-generated summary
This study investigated the utility of serial CA 125 measurements in monitoring endometriosis among infertile women.
One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works
Abstract
To evaluate the potential use of CA 125 concentrations in monitoring women with endometriosis, serial determinations were correlated with the clinical course of the disease and pregnancy rates. Preoperative CA 125 concentrations were obtained in 134 consecutive infertile women with endometriosis. Seventy-six (57%) women had values greater than or equal to 16 U/ml and were followed up for 18 months. At the 6-, 12-, and 18-month intervals, pregnancies occurred in 18 of 45 (30%), 14 of 24 (58%), and 5 of 12 (42%) women in the good prognosis group, respectively; pregnancy rates in the poor prognosis group were 1 of 31 (3%), 2 of 33 (6%), and 0 of 26 (0%) women (p less than 0.001). Changes in the CA 125 values correlated with the surgical findings in 24 of the 26 women (92%) who had a second-look operative procedure. The study supports the use of serial CA 125 concentrations to assist in the management of women with endometriosis.
My notes (saved in your browser only)
Condition tags
MeSH descriptors
Citation neighborhood (2-hop)
Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]
References (12)
- CA-125 in women with endometriosis via openalex
- CA-125 in Women with Endometriosis via openalex
- CA-125 levels in endometriosis via openalex
- Recurrent endometriosis: incidence, management, and prognosis via openalex
- W2053154970 via openalex
- W2283760758 via openalex
- W73242332 via openalex
- W2408957827 via openalex
- W2415755045 via openalex
- W2477008945 via openalex
- W170259557 via openalex
- W42372792 via openalex
Cited by (15)
- Prevalence of endometriosis among adolescent school girls with severe dysmenorrhea: A cross sectional prospective study 2015
- Pathophysiology of Infertility in Endometriosis 2011
- Clinical Aspects of Endometriosis 2010
- Semi-invasive Diagnosis of Endometriosis Doctoral Thesis 2010
- Biomarkers of endometriosis 2008
- Endometriomas de la pared abdominal. Revisión de una serie de 17 casos 2008
- The effect of endometriosis, cycle stage, lymphocyte suppression and pregnancy on CA-125 levels in peritoneal fluid and serum in baboons 2005
- Abdominal wall endometriosis: a diagnostic dilemma for surgeons 2005
- Chemical assay of iron in ovarian cysts: a new diagnostic method to evaluate endometriotic cysts 1998
- Correlation of basal menses CA-125 levels and 6 month pregnancy rates in women undergoing treatments for infertility without assisted reproductive methods 1997
- Evaluation of serum CA 125 concentrations as predictors of pregnancy with human in vitro fertilization 1996
- Clinical evaluation of CA-125 concentrations as a prognostic factor for pregnancy in infertile women with surgically treated endometriosis 1995
- Serum CA-125 concentration in endometriosis patients: role of pelvic and peritoneal irritation 1994
- Endometriosis in the adolescent and teenage female 1993
- Endometriosis: the host response 1993
Source provenance
- europepmc
- last seen: 2026-10-15T06:08:49.021275+00:00
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-10-08T21:12:41.142639+00:00
- unpaywall
- last seen: 2026-10-15T06:24:24.424788+00:00
License: CC0
· commercial use OK