Benign or Malignant Ovarian Neoplasms and Ovarian Endometriomas

Takahashi K, K Takahashi, Kentaro Takahashi, Kurioka H, Hiroko Kurioka, H Kurioka, M Irikoma, Maki Irikoma, Irikoma M, T Ozaki, Ozaki T, Tomoya Ozaki, Kanasaki H, Haruhiko Kanasaki, H Kanasaki, Miyazaki K, Kohji Miyazaki, K Miyazaki
The Journal of the American Association of Gynecologic Laparoscopists · 2001 · vol. 8(2) , pp. 278–284 · doi:10.1016/s1074-3804(05)60591-9 · PMID:11342738 · W1996839909
article OA: closed CC0 ⤵ 17 in-corpus citations
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This paper discusses the differentiation between benign and malignant ovarian neoplasms and ovarian endometriomas.

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Abstract

Study objectiveTo investigate clinical features and biologic behavior of ovarian cancer that might be closely related to endometrioma and/or endometriosis.DesignRetrospective study (Canadian Task Force classification II-2).SettingUniversity hospital.PatientsAll 324 women who were operated for endometriomas and/or ovarian tumors 5 cm or greater in diameter between January 1988 and December 1997.InterventionOne hundred twelve women underwent laparoscopic surgery and 212 had laparotomy.Measurements and main resultsAll tissues were evaluated histologically. Clinical examinations including ultrasound and serum tumor makers were performed in all patients preoperatively. No malignancies were found at laparoscopic surgery (76 endometriomas, 36 ovarian tumors). The frequency of endometriosis in benign, borderline malignant, and malignant tumors was 9.7%, 12.5%, and 11.4%, respectively. Endometriosis was present most frequently (40%) in women with endometrioid adenocarcinoma. It was present in 81 patients with endometriomas and 25 with ovarian neoplasms. Of these, nine women (8.5%) had malignant tumors, including borderline malignancy. Among patients with malignant tumors, those without endometriosis were significantly older (mean +/- SD age 54.9 +/- 16.2 yrs) than those with endometriosis elsewhere in the pelvis (45.9 +/- 8.9 yrs).ConclusionEndometriosis may be closely related to ovarian tumors such as endometrioid adenocarcinoma. Surgeons should be aware of this possibility, and candidates for laparoscopic surgery should be carefully selected based on preoperative evaluations.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Ovarian Diseases Ovarian Neoplasms CA-125 Antigen CA-125 Antigen Endometriosis Endometriosis Endometriosis Endometriosis Female Humans Laparoscopy Ovarian Diseases Ovarian Diseases Ovarian Diseases Ovarian Diseases Ovarian Neoplasms Ovarian Neoplasms Ovarian Neoplasms Ovarian Neoplasms

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Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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