Endometriosis with FDG uptake on PET

Louis Jeffry, Jeffry L, Kerrou K, Khaldoun Kerrou, S. Camatte, Camatte S, Sophie Camatte, U. Metzger, Metzger U, Ulrike Metzger, Loic Lelièvre, Loïc Lelièvre, Lelièvre L, Jean-Noel Talbot, Jean‐Noël Talbot, Fabrice Lecuru, Fabrice Lécuru, Lecuru F
European journal of obstetrics, gynecology, and reproductive biology · 2004 · vol. 117(2) , pp. 236–239 · doi:10.1016/j.ejogrb.2004.04.034 · PMID:15541863 · W1985076462
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This paper investigates the presence and patterns of fluorodeoxyglucose (FDG) uptake in women diagnosed with endometriosis.

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Abstract

BackgroundThe value of [18F]fluorodeoxyglucose positron emission tomography (FDG-PET) uptake in endometriosis has not yet been extensively reported.Case reportA 32-year-old woman was examined to find an explanation for right pelvic pain associated with right subcostal pain. A computerised tomography (CT) scan was compatible with a haemangioma or a focus of endometriosis in the liver. Transvaginal sonography and magnetic resonance imaging (MRI) showed a complex ovarian cyst on the left. Blood CA125 levels were elevated. FDG-PET revealed a focus of uptake in the right paravesical area. Laparoscopy showed a left endometrioma associated with diffuse inflammatory pelvic adhesions. After surgery and 3 months GnRH agonist treatment the pain had disappeared and neither MRI nor FDG-PET showed any pelvic abnormality. The patient subsequently presented with dyspareunia and rectal pain resulting from a right uterosacral nodule and a rectal nodule. These were resected laparoscopically. After a 1-year follow-up, the patient is doing well.ConclusionEndometriosis can give rise to false-positive results on FDG-PET. However, the FDG uptake in this particular case of endometriosis seems to have been due to inflammation rather than to a cyst. This report highlights the relationship between some of the biological features of endometriosis and some observed in neoplastic lesions.

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Condition tags

endometriosischronic_pelvic_pain

MeSH descriptors

Endometriosis Fluorodeoxyglucose F18 Positron-Emission Tomography Radiopharmaceuticals Abdominal Pain Abdominal Pain Adult CA-125 Antigen CA-125 Antigen Endometriosis Endometriosis Endometriosis Endosonography Female Gonadotropin-Releasing Hormone Gonadotropin-Releasing Hormone Gynecologic Surgical Procedures Hormones Hormones Humans

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Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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