Endometriosis with FDG uptake on PET

Case report OA: closed CC0 ⤵ 25 in-corpus citations
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This paper investigates the presence and patterns of fluorodeoxyglucose (FDG) uptake in women diagnosed with endometriosis.

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Abstract

BACKGROUND: The value of [18F]fluorodeoxyglucose positron emission tomography (FDG-PET) uptake in endometriosis has not yet been extensively reported. CASE REPORT: A 32-year-old woman was examined to find an explanation for right pelvic pain associated with right subcostal pain. A computerised tomography (CT) scan was compatible with a haemangioma or a focus of endometriosis in the liver. Transvaginal sonography and magnetic resonance imaging (MRI) showed a complex ovarian cyst on the left. Blood CA125 levels were elevated. FDG-PET revealed a focus of uptake in the right paravesical area. Laparoscopy showed a left endometrioma associated with diffuse inflammatory pelvic adhesions. After surgery and 3 months GnRH agonist treatment the pain had disappeared and neither MRI nor FDG-PET showed any pelvic abnormality. The patient subsequently presented with dyspareunia and rectal pain resulting from a right uterosacral nodule and a rectal nodule. These were resected laparoscopically. After a 1-year follow-up, the patient is doing well. CONCLUSION: Endometriosis can give rise to false-positive results on FDG-PET. However, the FDG uptake in this particular case of endometriosis seems to have been due to inflammation rather than to a cyst. This report highlights the relationship between some of the biological features of endometriosis and some observed in neoplastic lesions.

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Condition tags

endometriosischronic_pelvic_pain

MeSH descriptors

Endometriosis Fluorodeoxyglucose F18 Fluorodeoxyglucose F18 Positron-Emission Tomography Radiopharmaceuticals Radiopharmaceuticals Abdominal Pain Abdominal Pain Abdominal Pain Adult Adult CA-125 Antigen CA-125 Antigen CA-125 Antigen Endometriosis Endometriosis Endometriosis Endometriosis Endosonography Endosonography

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (14)

Cited by (26)

Source provenance

europepmc
last seen: 2026-10-16T06:09:50.462052+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-10-08T21:02:47.667321+00:00
License: CC0 · commercial use OK