Endometriose

In: Gynäkologische Endokrinologie · 2013 · vol. 11(2) , pp. 115–128 · doi:10.1007/s10304-013-0556-4 · W2329213932
article OA: closed CC0 ⤵ 1 in-corpus citation
Full text JSON View on OpenAlex View at publisher
AI-generated summary by gemini-2.5-flash-lite+body, 2026-06-12

This review discusses endometriosis, a common benign condition in women, its delayed diagnosis despite characteristic symptoms, diagnostic methods, and treatment options including surgery and medication.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

AI-generated deep summary by claude@2026-06, 2026-06-12 · read from full text

The paper summarizes endometriosis as a common benign condition in reproductive-age women, emphasizing the characteristic symptom pattern (especially dysmenorrhea with chronic pelvic pain and other related symptoms) and the ongoing delay to correct diagnosis. It states that simple rectovaginal examination methods can be indicative, while laparoscopy should be pursued early to confirm diagnosis, and it describes postoperative recurrence prevention and recurrent-case treatment as individualized. For recurrence management, it notes options including recurrence operations and pharmacological approaches such as pain medications, progestins, oral contraceptives in long-cycle regimens, and GnRH analogues. The paper does not explicitly name study limitations, and it is presented as an overview rather than reporting new original population-based methods. This paper is centrally about endometriosis — it provides a diagnostic and management-focused overview of endometriosis.

Read from the paper's body, not the abstract. Not a substitute for reading the paper. No clinical advice. How this works

Full text 7,097 characters · extracted from oa-doi-fallback · click to expand
Zusammenfassung Die Endometriose zählt zu den häufigsten gutartigen Erkrankungen der geschlechtsreifen Frau. Trotz des charakteristischen Symptoms der Dysmenorrhö – häufig in Kombination mit Begleitsymptomen wie chronischen Unterbauchschmerzen, Dyschezie, Dysurie und Dyspareunie – dauert es immer noch zu lange, bis die Diagnose gestellt wird. Einfache Methoden der rektovaginalen Untersuchung sind hinweisend. Die Laparoskopie sollte zur Diagnosesicherung frühzeitig angestrebt werden. Eine postoperative Rezidivprophylaxe kann – bei fehlendem Kinderwunsch – sinnvoll sein. In der Rezidivsituation gilt es, individuell und im Konsens mit der Patientin das optimale Behandlungskonzept zu finden. Neben Rezidivoperationen kommen medikamentöse Maßnahmen zum Einsatz: neben Schmerzmedikamenten Gestagene, orale Kontrazeptiva im Langzyklus sowie Gonadotropin-releasing-Hormon(GnRH)-Analoga. Abstract Endometriosis is one of the most common benign diseases of the mature woman. In spite of characteristic symptoms like dysmenorrhea—often in combination with accompanying symptoms such as chronic pelvic pain, dyschezia, dysuria and dyspareunia—it still takes too long for the correct diagnosis to be made. Simple methods like rectovaginal exam are indicative. Laparoscopy to confirm the diagnosis should be sought at an early stage. Postoperative recurrence prevention can—if there is no desire for children—make sense. In recurrent endometriosis, therapy must be individually made in consensus with the patient to find the optimal treatment plan. Besides recurrence operations, pharmacological treatment is often used. In addition to pain medications, progestins, oral contraceptives in long-cycle and gonadotropin-releasing hormone (GnRH) analogues are used. Literatur Knapp VJ (1999) How old is endometriosis? Late 17th- and 18th-century European descriptions of the disease. Fertil Steril 72:10–14 Kiple K (1993) The Cambridge world history of human disease. Cambridge University Press, Cambridge McGrew R (1985) Encyclopedia of medical history. McGraw-Hill, New York Rousset-Jablonski C et al (2011) Catamenial pneumothorax and endometriosis-related pneumothorax: clinical features and risk factors. Hum Reprod 26:2322–2329 Mahmood TA, Templeton A (1991) Prevalence and genesis of endometriosis. Hum Reprod 6:544–549 Moen MH, Schei B (1997) Epidemiology of endometriosis in a Norwegian county. Acta Obstet Gynecol Scand 76:559–562 Vigano P et al (2004) Endometriosis: epidemiology and aetiological factors. Best Pract Res Clin Obstet Gynaecol 18:177–200 Renner SP et al (2006) Endometriose. Geburts Frauenheilk 66:R61–R88 Meyer R (1919) Über den Stand der Frage der Adenomyositis, Adenomyome im Allgemeinen und insbesondere über Adenomyositis seroepithelialis und Adenomyometritis sarcomatosa. Zentralbl Gynakol 43:745–750 Sampson JA (1927) Metastatic or embolic endometriosis, due to the menstrual dissemination of endometrial tissue into the venous circulation. Am J Pathol 3:93–110.43 D’Hooghe TM (1997) Clinical relevance of the baboon as a model for the study of endometriosis. Fertil Steril 68:613–625 Dehoux JP et al (2011) Is the baboon model appropriate for endometriosis studies? Fertil Steril 96:728–733.e3 Burghaus SKP, Fasching PA, Engel A et al (2011) Risk factors for endometriosis in a German case-control study. Geburtshilfe Frauenheilkunde 71:1073–1079 Leslie C et al (2013) Is the detection of endometrial nerve fibers useful in the diagnosis of endometriosis? Int J Gynecol Pathol 32:149–155 Aghaey Meibody F et al (2011) Diagnosis of endometrial nerve fibers in women with endometriosis. Arch Gynecol Obstet 284:1157–1162 Xu L, Pfaltz CR, Arnold W (1993) Human leukocyte antigens in patients with inner ear diseases of unknown etiology. ORL J Otorhinolaryngol Relat Spec 55:125–134 Xu H et al (2013) Vascular endothelial growth factor C is increased in endometrium and promotes endothelial functions, vascular permeability and angiogenesis and growth of endometriosis. Angiogenesis (im Druck) Al-Jefout M et al (2009) Diagnosis of endometriosis by detection of nerve fibres in an endometrial biopsy: a double blind study. Hum Reprod 24:3019–3024 Cahill DJ (2002) What is the optimal medical management of infertility and minor endometriosis? Analysis and future prospects. Hum Reprod 17:1135–1140 Hassa H et al (2009) Cytokine and immune cell levels in peritoneal fluid and peripheral blood of women with early- and late-staged endometriosis. Arch Gynecol Obstet 279:891–895 Sokolov DI et al (2005) Study of cytokine profile and angiogenic potential of peritoneal fluid in patients with external genital endometriosis. Bull Exp Biol Med 140:541–544 Khorram O et al (1993) Peritoneal fluid concentrations of the cytokine RANTES correlate with the severity of endometriosis. Am J Obstet Gynecol 169:1545–1549 Leyendecker G et al (2004) Uterine peristaltic activity and the development of endometriosis. Ann N Y Acad Sci 1034:338–355 Leyendecker G et al (2002) Endometriosis results from the dislocation of basal endometrium. Hum Reprod 17:2725–2736 Kunz G et al (2000) Structural abnormalities of the uterine wall in women with endometriosis and infertility visualized by vaginal sonography and magnetic resonance imaging. Hum Reprod 15:76–82 Leyendecker G et al (1998) Endometriosis: a dysfunction and disease of the archimetra. Hum Reprod Update 4:752–762 Leyendecker G et al (1996) Uterine hyperperistalsis and dysperistalsis as dysfunctions of the mechanism of rapid sperm transport in patients with endometriosis and infertility. Hum Reprod 11:1542–1551 Ulrich U et al (2010) Interdisziplinäre S1-Leitlinie: Diagnostik und Therapie der Endometriose. AWMF-Leitlinie Nr. 015/045 Kennedy S et al (2005) ESHRE guideline for the diagnosis and treatment of endometriosis. Hum Reprod 20:2698–2704 Alborzi S et al (2004) A prospective, randomized study comparing laparoscopic ovarian cystectomy versus fenestration and coagulation in patients with endometriomas. Fertil Steril 82:1633–1637 Alhamdan D et al (2010) Mirena intra-uterine system: does it improve long term symptoms in women with chronic pelvic pain and/or endometriosis after laparoscopy? A multicentre randomized controlled trial. Rev Recent Clin Trials 5:143–146 Chapron C et al (2011) Oral contraceptives and endometriosis: the past use of oral contraceptives for treating severe primary dysmenorrhea is associated with endometriosis, especially deep infiltrating endometriosis. Hum Reprod 26:2028–2035 Interessenkonflikt Der korrespondierende Autor gibt für sich und seine Koautoren an, dass kein Interessenkonflikt besteht. Author information Authors and Affiliations Corresponding author Rights and permissions About this article Cite this article Renner, S., Burghaus, S., Hackl, J. et al. Endometriose. Gynäkologische Endokrinologie 11, 115–128 (2013). https://doi.org/10.1007/s10304-013-0556-4 Published: Issue date: DOI: https://doi.org/10.1007/s10304-013-0556-4 Schlüsselwörter - Dysmenorrhö - Chronische Unterbauchschmerzen - Laparoskopie - Tief infiltrierende Endometriose - Gonadotropin-releasing-Hormon

Text is read by the "Ask this paper" AI Q&A widget below. Extraction quality varies by source — PMC NXML preserves structure cleanly, OA-HTML may include some navigation residue, and OA-PDF can have broken hyphenation. The publisher copy (via DOI) is the canonical version.

My notes (saved in your browser only)

Ask this paper AI returns verbatim quotes from the full text · source: oa-doi-fallback

Answers must be backed by verbatim quotes from this paper's full text. Hallucinated quotes are dropped automatically; if no verbatim passage answers the question, we say so. How this works

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (31)

Cited by (1)

Source provenance

openalex
last seen: 2026-06-10T17:14:06.276822+00:00
unpaywall
last seen: 2026-08-18T06:27:49.008893+00:00
License: CC0 · commercial use OK