Use of oral contraceptives in women with endometriosis before assisted reproduction treatment improves outcomes

de Ziegler D, Dominique de Ziegler, Vanessa Gayet, Gayet V, Aubriot FX, François Xavier Aubriot, F. X. Aubriot, Patricia Fauque, Fauque P, Isabelle Streuli, Jean Philippe Wolf, Wolf JP, J. de Mouzon, Jacques de Mouzon, De Mouzon J, Charles Chapron, Chapron C
Fertility and sterility · 2010 · vol. 94(7) , pp. 2796–2799 · doi:10.1016/j.fertnstert.2010.05.056 · PMID:20663495 · W2048769205
RCT OA: bronze CC0 ⤵ 84 in-corpus citations
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⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-07 ⓘ

This study investigated the impact of oral contraceptive use in women with endometriosis prior to assisted reproduction and found improved treatment outcomes.

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Abstract

In women with endometriosis, including those with endometriomas, 6 to 8 weeks of continuous use of oral contraception (OC) before assisted reproduction treatment (ART) maintains ART outcomes comparable with the outcomes of age-matched controls without endometriosis. In contrast, ART outcomes are markedly compromised in endometriosis patients who are not pretreated with OC. Ovarian responsiveness to stimulation was not altered by 6 to 8 weeks' use of pre-ART OC, including in poor responders with endometriomas.

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Condition tags

endometriosis

MeSH descriptors

Contraceptives, Oral Endometriosis Reproductive Techniques, Assisted Reproductive Techniques, Assisted Uterine Diseases Adult Adult Combined Modality Therapy Combined Modality Therapy Contraceptives, Oral Contraceptives, Oral Drug Administration Schedule Drug Administration Schedule Endometriosis Endometriosis Endometriosis Female Female Gonadotropin-Releasing Hormone Gonadotropin-Releasing Hormone

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (22)

Cited by (50)

Source provenance

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License: CC0 · commercial use OK