Impact of assisted hatching on ART outcome in women with endometriosis

Nadir Ciray H, H Nadir Ciray, H. Nadir Çıray, Bener F, Faruk Bener, Levent Karagenç, Ulun Uluğ, Ulun Ulug, Bahçeci M, Mustafa Bahçeci
Human Reproduction · 2005 · vol. 20(9) , pp. 2546–2549 · doi:10.1093/humrep/dei064 · PMID:15905297 · W2096699259
article OA: bronze CC0 ⤵ 5 in-corpus citations
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This randomized study found that laser-assisted hatching did not improve pregnancy or implantation rates for embryos obtained from women with endometriosis compared to intact embryos.

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Abstract

BACKGROUND: Assisted hatching can improve the implantation rate in cycles with poor outcome. The impact of assisted hatching in embryos from women with endometriosis is not known. Therefore, the hypothesis that the implantation potential of embryos obtained from women with endometriosis can be improved with assisted hatching was tested. METHODS: In a prospective randomized study, transfer embryos obtained from 60 women with endometriosis were hatched using a laser system and compared to embryos obtained from patients with the same diagnosis which were left intact (n = 30). RESULTS: The characteristics of cycles were similar between groups. The pregnancy (40% zona intact, 28.3% assisted hatching), and implantation rates (19.4% zona intact, 17.8% assisted hatching) did not differ in endometriosis cycles regardless of assisted hatching. CONCLUSION: Assisted hatching does not improve outcome in women with endometriosis undergoing assisted reproduction.

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Condition tags

endometriosis

MeSH descriptors

Embryo Implantation Endometriosis Infertility, Female Pregnancy Outcome Reproductive Techniques, Assisted Adult Endometriosis Female Humans Infertility, Female Infertility, Female Pregnancy Prospective Studies Zona Pellucida

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (30)

Cited by (5)

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License: CC0 · commercial use OK