Perspectives of New Therapies for Endometriosis

Jenny Valentina Garmendia, Jenny V Garmendia, Juan Bautista De Sanctis, Juan B De Sanctis
Recent patents on endocrine, metabolic & immune drug discovery · 2012 · vol. 6(3) , pp. 218–223 · doi:10.2174/187221412802481702 · PMID:22694252 · W2320565135
article OA: closed CC0 ⤵ 1 in-corpus citation
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⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

This paper reviews new pharmacological approaches and patented therapies under development to treat endometriosis, an inflammatory disease impacting fertility.

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Abstract

Endometriosis is an inflammatory disease characterized by the presence of endometrial glandular epithelial and stromal cells growing in the extra-uterine environment. The disease affects: ovarian function, oocyte quality, embryo development and implantation, and uterine function resulting in infertility or spontaneous pregnancy loss. Even though the world’s prevalence is above 10 %, an effective treatment has not yet been found. New pharmacological approaches have been designed and patented that could serve as future therapies for this disease. Keywords: Androgens, coagulation, endometriosis, fertility, GnHR, inflammation, progesterone, signal transduction.

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Condition tags

mesh:D004715endometriosisinfertility

MeSH descriptors

Drug Discovery Endometriosis Women's Health Drug Design Drug Discovery Endometriosis Female Humans Patents as Topic Women's Health

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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License: CC0 · commercial use OK