Maternal and newborn outcomes in patients with endometriosis-associated infertility

E. N. Tishchenko, Н. В. Артымук, О. А. Зотова, Лариса Николаевна Данилова
In: Fundamental and Clinical Medicine · 2024 · vol. 9(3) , pp. 66–73 · doi:10.23946/2500-0764-2024-9-3-66-73 · W4402986342
article OA: diamond CC0 ⤵ 2 in-corpus citations
🔓 Open OA copy View on OpenAlex View at publisher
⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

Pregnancy in women with endometriosis-associated infertility was significantly more complicated by placenta previa, uterine inertia, retained placenta, hypotonic bleeding, and cesarean delivery compared to controls.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

⚙ AI-generated deep summary by claude@2026-06, 2026-06-07 ⓘ

The study retrospectively compared maternal and newborn outcomes in 115 women with histologically verified endometriosis-associated infertility versus 250 women without endometriosis in a case-control design. Compared with controls, the endometriosis-associated infertility group had significantly higher rates of placenta previa (5.2% vs 1.2%), cesarean delivery (49.6% vs 13.2%), and intrapartum complications including uterine dysfunction/weak labor activity, retained placental membranes, and hypotonic bleeding. Newborn outcomes (birth weight, Apgar scores at 1 and 5 minutes) and length of hospital stay did not differ significantly between groups. The paper explicitly notes limitations typical of retrospective case-control studies and calls for further expanded research; This paper is centrally about endometriosis — it examines pregnancy and delivery outcomes specifically in women with endometriosis-associated infertility.

Read from the paper's body, not the abstract. Not a substitute for reading the paper. No clinical advice. How this works

Abstract

Aim . To identify the characteristics of pregnancy and childbirth in women with endometriosis-associated infertility (EAI). Materials and Methods. Here we performed retrospective case-control study which included 115 women with histologically verified endometriosis and 250 women without this condition. Statistical analysis was conducted using the IMB SPSS Statistics 20 software package. The data distribution was assessed using the Kolmogorov-Smirnov test. Quantitative data are presented as median (Me) and interquartile range (Q1 – Q3) using the Mann-Whitney test. The level of statistical significance for testing the null hypothesis was set at p < 0.05. Results . Pregnancy in patients with EAI was statistically significantly more often complicated by placenta previa compared to the control group: 6 (5.2%) versus 3 (1.2%) (p = 0.031). Patients with EAI were delivered via cesarean section in 49.6% of cases, compared to 13.2% in those without EAI (p < 0.001). Labor in women with EAI was statistically significantly more often complicated by uterine inertia (hypotonic labor, 7.0% versus 2.4% in those without EAI, p = 0.043), retained placenta (4.3% vs 0.4%, p = 0.013); and hypotonic bleeding (3.5% vs 0.4%, p = 0.036). Maternal and neonatal outcomes including birth weight, Apgar scores at 1 and 5 minutes, and the duration of hospital stay did not differ significantly between the groups. Conclusions. Patients with EAI are characterized by a complicated course of pregnancy and childbirth with a higher incidence of placenta previa, abnormal labor, hypotonic bleeding, retained placenta, and cesarean delivery. Hence, the development of respective therapeutic and preventive measures is required to prevent these complications.

My notes (saved in your browser only)

Condition tags

endometriosisinfertility

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (23)

Cited by (2)

Source provenance

openalex
last seen: 2026-06-10T17:14:06.276822+00:00
License: CC0 · commercial use OK