Inflammation and endometriosis

Lingli Jiang, Zhou Liu, Yan Yan, Ying Wang
Frontiers in bioscience (Landmark edition) · 2016 · vol. 21(5) , pp. 941–948 · doi:10.2741/4431 · PMID:27100482 · W2331250137
review OA: closed CC0 ⤵ 102 in-corpus citations
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This review examines the role of inflammatory processes in the pathogenesis of endometriosis, a condition characterized by endometrial tissue outside the uterus affecting 5-10% of reproductive-aged women.

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Abstract

Endometriosis is defined by presence of endometrial glands and stroma outside the uterine cavity and it affects approximately 5%-10% of women of reproductive age. Although endometriosis is usually considered to be due to retrograde menstruation, the true pathogenesis of this disease remains poorly understood. Endometriosis is associated with an inflammatory response and this inflammation leads to endothelial dysfunction and might even lead to carcinogenesis. Here, we review our current understanding of the role of inflammatory processes in the pathogenesis of endometriosis.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Inflammation Animals Chemokine CCL5 Chemokine CCL5 Endometriosis Endometriosis Endometriosis Female Humans Inflammation Inflammation Inflammation Lymphocyte Activation T-Lymphocyte Subsets T-Lymphocyte Subsets

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

Cited by (50)

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License: CC0 · commercial use OK