Evaluation of monocyte chemotactic protein-1 level in serum of fertile and infertile women

In: International journal of health sciences · 2022 · pp. 10498–10504 · doi:10.53730/ijhs.v6ns2.7753 · W4281622663
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This study evaluated serum monocyte chemotactic protein-1 levels in fertile and infertile women to investigate its role in female infertility.

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AI-generated deep summary by claude@2026-06, 2026-06-09 · read from full text

This paper compares serum monocyte chemotactic protein-1 (MCP-1) levels between fertile women and infertile women, framing infertility as a reproductive disorder potentially linked to inflammatory and other medical causes. The key reported outcome is an evaluation of whether MCP-1 differs between the fertile versus infertile groups, with MCP-1 presented as a chemotactic cytokine relevant to immune cell recruitment. A major limitation is that the abstract text provided does not specify the study design details (e.g., sample size, assays, and statistical comparisons) or whether specific infertility etiologies were distinguished. Relevance to endometriosis: the broader infertility context in the paper includes endometriosis-related infertility among listed causes, though this paper’s main topic is MCP-1 level comparison between fertile and infertile women rather than endometriosis-specific mechanisms.

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Abstract

Infertility is a disease of the reproductive system characterized by inability to achieve pregnancy after 12 or more months of regular unprotected sexual intercourse (Venkatesh et al., 2014). Female infertility, as a complex disorder, may be caused by medical conditions including pelvic inflammatory disease, endometriosis related infertility, ovulatory disorders, tubal factor infertility, and unexplained infertility(Gupta et al., 2014). Infertility affect approximately nine to fifteen percent of the childbearing population, and 55% of these influenced will seek medical help to achieve their desire to have children (Boivin et al., 2011).
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Keywords

evaluation, monocyte chemotactic protein, fertile, infertile womenAbstract Infertility is a disease of the reproductive system characterized by inability to achieve pregnancy after 12 or more months of regular unprotected sexual intercourse (Venkatesh et al., 2014). Female infertility, as a complex disorder, may be caused by medical conditions including pelvic inflammatory disease, endometriosis related infertility, ovulatory disorders, tubal factor infertility, and unexplained infertility(Gupta et al., 2014). Infertility affect approximately nine to fifteen percent of the childbearing population, and 55% of these influenced will seek medical help to achieve their desire to have children (Boivin et al., 2011). Downloads

References

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