Long-term fertility after laparoscopy for endometriosis-associated pelvic pain in young adult women
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This study investigated long-term fertility rates in young adult women who underwent laparoscopy for endometriosis-associated pelvic pain.
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Abstract
STUDY OBJECTIVE: To describe the long-term fertility outcomes in young patients with endometriosis-associated pelvic pain treated with laparoscopic surgery.
DESIGN: Retrospective case series (Canadian Task Force classification II-2).
SETTING: Tertiary care hospital.
PATIENTS: Women aged 18 to 25 years who underwent laparoscopic surgery between 2000 and 2005 at the Cleveland Clinic Foundation solely to treat endometriosis-associated pelvic pain.
INTERVENTIONS: Patients answered a telephone or mail survey questionnaire assessing fertility outcome after surgery.
MEASUREMENTS AND MAIN RESULTS: Twenty-eight of 74 eligible patients (37.8%) were enrolled in the study. With a median (interquartile range) age of 23.5 (1.5) years at follow-up, these patients completed the telephone or postal questionnaire to assess fertility outcomes at follow-up of 102.5 (16.6) months. In most participants the diagnosis was less advanced endometriosis (stage I, 60.7%; stage II, 28.6%). Twenty women (71.4%) had at least 1 pregnancy during follow-up that resulted in a live birth, of which >80% were spontaneous without the use of assisted reproductive technologies.
CONCLUSION: Long-term pregnancy rates are excellent in young women undergoing laparoscopic surgery to treat pelvic pain. However, a future prospective study is needed to determine whether laparoscopy has any hindrance on future fertility.
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Cited by (14)
- In the thicket of fears, doubts, and murky facts: some reflections on treatment modalities for endometriosis-associated pain 2023
- Infertilidad y endometriosis 2020
- Reproductive capacity and recurrence of disease after surgery for moderate and severe endometriosis. 2020
- Laparoscopic Surgery in Adolescent Endometriosis 2020
- Adolesan Endometriozis 2020
- Reproductive capacity and recurrence of disease after surgery for moderate and severe endometriosis – a retrospective single center analysis 2020
- Reproductive capacity and recurrence of disease after surgery for moderate and severe endometriosis - a retrospective single center analysis 2020
- Endometriosis in Adolescence: Challenges and Opportunities for Managing Future Infertility 2018
- A focus on the distinctions and current evidence of endometriosis in adolescents 2018
- Endometriosis in Adolescents: A Systematic Review 2017
- Inhibitory effect of curcumin in human endometriosis endometrial cells via downregulation of vascular endothelial growth factor 2017
- Trauma and endometriosis. A review. May we explain surgical phenotypes and natural history of the disease? 2017
- Adolescent Endometriosis 2015
- A Comparison of Treatment Modalities in 69 Patients with Endometriosis and/or Endometrioma and Review of the Literature 2015
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