International journal of reproductive biomedicine

Int J Reprod Biomed · ISSN (print) 2476-4108 · 218 papers in corpus
rct 2025
doi:10.18502/ijrm.v23i12.20712 ·PMID:41783725

BACKGROUND: Polycystic ovary syndrome (PCOS) is a leading cause of anovulatory infertility. In women undergoing frozen embryo transfer, the method of endometrial preparation (hormone replacement therapy [HRT] or mild ovarian stimulation [MO…

rct 2025
doi:10.18502/ijrm.v23i12.20716 ·PMID:41783731

BACKGROUND: In women with poor ovarian response (POR), the quantity and quality of oocytes produced by the ovaries decrease, resulting in poor-quality embryos. Ovarian stimulation, by increasing the number of oocytes and embryos, improves i…

observational 2025
doi:10.18502/ijrm.v23i9.20163 ·PMID:41306467

BACKGROUND: Endometriosis is a common disease of the female genital system. Pelvic magnetic resonance imaging (MRI) is the best non-invasive diagnostic method for evaluating endometriosis. OBJECTIVE: This study aims to compare the findings…

observational 2025
doi:10.18502/ijrm.v22i12.18066 ·PMID:39968362

BACKGROUND: Endometriosis (EM) is a condition that causes infertility with decreasing uterine receptivity. It is reported that it affects about 20-25% of all infertile women. Some genetic markers play a crucial role in pathogenesis and infe…

observational 2025
doi:10.18502/ijrm.v23i12.20715 ·PMID:41783727

BACKGROUND: Infertility affects millions of couples worldwide. The number of morphologically normal oocytes (MNO) is a key determinant of assisted reproductive technology success. Accurate identification of influencing factors is limited by…

other 2025
doi:10.18502/ijrm.v23i11.20547 ·PMID:41782694

BACKGROUND: Polycystic ovarian syndrome (PCOS) is a common endocrine disorder in women, associated with insulin resistance, ovulatory dysfunction, hyperandrogenism, and inflammation. Current treatments often focus on symptoms rather than un…

observational 2025
doi:10.18502/ijrm.v23i2.18484 ·PMID:40371359

BACKGROUND: Endometrial compaction (EC) is an ultrasound evaluation method that may predict assisted reproductive technology outcomes. OBJECTIVE: This study aimed to assess the impact of EC on assisted reproductive technology outcomes in f…

rct 2025
doi:10.18502/ijrm.v23i3.18775 ·PMID:40567909

BACKGROUND: Women with low ovarian reserve are the capable part of people who refer to infertility centers, this study compares 2 treatment protocols in cases with low ovarian reserve. OBJECTIVE: This study aimed to compare the efficacy of…

nonrandomized-trial 2025
doi:10.18502/ijrm.v23i2.18494 ·PMID:40371363

BACKGROUND: Studies have shown that endometriosis significantly has a negative impact on women's mental health and quality of life (QoL), resulting in these participants experiencing a diminished QoL. OBJECTIVE: This study aimed to evaluat…

rct 2025
doi:10.18502/ijrm.v23i9.20158 ·PMID:41306463

BACKGROUND: Recurrent implantation failure in assisted reproductive technology is a major challenge. Intrauterine human chorionic gonadotropin (hCG) infusion and hyaluronic acid enriched embryo transfer media have shown individual effects, …

observational 2025
doi:10.18502/ijrm.v23i2.18496 ·PMID:40371358

BACKGROUND: Polycystic ovarian syndrome (PCOS) is a complex disorder that affects the endocrine, metabolic, and reproductive systems. While controlled ovarian hyperstimulation can increase the number of oocytes retrieved and improve the num…

observational 2025
doi:10.18502/ijrm.v22i11.17819 ·PMID:39866586

BACKGROUND: Endometrioma, a common manifestation of endometriosis, often indicates the severity of the disease. In vitro fertilization and embryo transfer (ET) are key therapeutic strategies for infertility associated with endometriosis. Ho…

observational 2025
doi:10.18502/ijrm.v23i5.19262 ·PMID:40989083

BACKGROUND: Obesity and metabolic syndrome (MetS), as components of excess body weight, have reached global epidemic levels. OBJECTIVE: The study aimed to investigate the features of the MetS course in men and women of reproductive age. M…

case-report 2025
doi:10.18502/ijrm.v22i11.17825 ·PMID:39866584

BACKGROUND: To introduce minimally invasive methods for the successful treatment of tubo-ovarian abscesses (TOAs), an antibiotic regimen was considered the first line of treatment. However, in some cases, this approach fails, and another in…

review 2025
doi:10.18502/ijrm.v23i9.20156 ·PMID:41306462

BACKGROUND: Elagolix, Linzagolix, and Relugolix, as oral gonadotropin-releasing hormone antagonists, have emerged as promising treatments for endometriosis-associated pain. OBJECTIVE: To evaluate pain intensity reduction as the primary out…

other 2025
doi:10.18502/ijrm.v23i10.20316 ·PMID:41438399

BACKGROUND: Infertility is the inability to conceive after a year of trying, resulting in unintentional childlessness. A clinical decision-support system can enhance diagnosis, reduce costs, improve access, and increase treatment accuracy. …

rct 2025
doi:10.18502/ijrm.v22i12.18065 ·PMID:39968367

BACKGROUND: Endometriosis is a chronic inflammatory condition associated with debilitating chronic pelvic pain that affects women's quality of life. Several drugs have been used to reduce pain and psychological distress associated with this…

review 2025
doi:10.18502/ijrm.v23i1.18188 ·PMID:40190457

According to the World Health Organization, 17.5% of the population suffers from infertility. This demonstrates the critical need to expand access to high-quality reproductive care and increase our understanding of the factors that contribu…

review 2025
doi:10.18502/ijrm.v23i5.19261 ·PMID:40989081

Several autoimmune and immunological disorders can cause infertility. About 10-20% of infertility cases are related to fetal-maternal immune factors. The use of immunological treatments in women with infertility is an emerging strategy. Tac…

other 2025
doi:10.18502/ijrm.v23i5.19265 ·PMID:40989079

BACKGROUND: Adenomyosis is a gynecological disorder characterized by the presence of endometrial tissue within the myometrium, with incidence rates ranging from 10-65% among women of reproductive age. OBJECTIVE: This study utilized transcr…

review 2024
doi:10.18502/ijrm.v22i5.16433 ·PMID:39091427

Endometriosis is a major health concern in women who have it. Unfortunately, there is no definitive cure except panhysterectomy with its sequelae including induction of premature menopause due to loss of ovaries. Therefore, revealing the ca…

observational 2024
doi:10.18502/ijrm.v22i4.16389 ·PMID:39035630

BACKGROUND: Some women experienced alterations in their menstrual cycles during the Coronavirus disease 2019 (COVID-19) pandemic. OBJECTIVE: This study aimed to evaluate the changes in menstrual cycles among Iranian women during the COVID-…

rct 2024
doi:10.18502/ijrm.v22i10.17668 ·PMID:39906088

BACKGROUND: Recurrent implantation failure (RIF) can be explained mainly by improper crosstalk between the embryo and endometrium. The T-helper1/T-helper2 profile balance influences effective embryo implantation. Endometrial immunomodulatio…

rct 2024
doi:10.18502/ijrm.v22i6.16793 ·PMID:39205923

BACKGROUND: Assisted reproductive technology (ART), offers hope for many infertile couples by increasing the chance of successful pregnancy. The success of in vitro fertilization depends on various factors, in which embryo transfer (ET) is …

observational 2024
doi:10.18502/ijrm.v22i6.16798 ·PMID:39205922

BACKGROUND: The association between endometriosis and the outcome of pregnancy is one of the interesting topics. Endometriosis-related pain is alleviated with pregnancy; however, it is known to cause adverse outcomes in pregnancy. The main …