The Journal of reproductive medicine

OBJECTIVE: To determine the prognostic significance of laparoscopy results for fertility outcome. STUDY DESIGN: Consecutive patients undergoing hysterosalpingography and laparoscopy for subfertility in our department between May 1985 and N…

OBJECTIVE: To examine psychosomatic aspects of vulvodynia (VD) in comparison with the chronic pelvic pain syndrome (CPPS). STUDY DESIGN: Sixty-seven VD patients and 97 CPPS patients were examined with psychological tests (Freiburg Personal…

Progesterone plays a crucial role in the coordination of endometrial breakdown as well as in the determination and regulation of menstrual blood loss and endometrial transudation of fluid. Furthermore, long-term exposure of the endometrium …

OBJECTIVE: To examine whether insulinlike growth factor I (IGF I), IGF II and IGF binding protein 3 (IGFBP 3) in serum and peritoneal fluid (PF) correlate with the presence and severity of endometriosis. STUDY DESIGN: Case-control study in…

BACKGROUND: Tuberculosis of the endometrium is usually associated with infertility. Once a patient is diagnosed with endometrial tuberculosis, she is almost certain to experience infertility; in vitro fertilization and embryo transfer offer…

OBJECTIVE: To review the impact of gonadotropin-releasing hormone agonists (GnRH-as) on bone mass in adolescents and options for GnRH-a with "add-back" for long-term therapy for adolescents with endometriosis not responding to conventional …

OBJECTIVE: To outline the optimal use of bone densitometry in women receiving gonadotropin releasing hormone (GnRH) agonist therapy. STUDY DESIGN: The use of bone densitometry during clinical trials of the use of GnRH agonists in endometri…

Use of preoperative gonadotropin-releasing hormone (GnRH) agonists may be beneficial in the case of laparoscopic surgery for large endometriomas. Further studies are necessary to confirm the claim that preoperative GnRH agonists facilitate …

OBJECTIVE: To understand why differences in gonadotropin releasing hormone (GnRH) agonist therapeutic protocols may affect their efficacy and safety profiles, to understand the important study design facets regarding the literature on GnRH …

OBJECTIVE: To determine the effect of danazol on in vitro fertilization-embryo transfer (IVF-ET) patients who failed to conceive in previous attempts despite having embryos with optimal morphology, whether endometriosis is present or not. …

Estrogen-dependent diseases often regress when estrogen production is reduced. Endometriosis is an estrogen-responsive disease, and the pelvic pain associated with it improves when estrogen production is reduced with bilateral oophorectomy …

OBJECTIVE: To explore the hypothesis that endometriosis is a disease not just because it exists but because it is functionally active. STUDY DESIGN: Qualitative research analyzing the morphologic appearances of endometriosis and the clinic…

While the debate rages on regarding how metabolic and immunologic changes fit into the pathophysiology of endometriosis, the clinician must nonetheless make decisions regarding treatment. This article examines the relevant literature, with …

OBJECTIVE: To critically assess the world literature on the efficacy and safety of the vaginal ring estradiol delivery system for the local treatment of urogenital atrophy due to hypoestrogenism. STUDY DESIGN: Published data over the past …

OBJECTIVE: To project the efficacy and economic consequence of short-term intranasal gonadotropin-releasing hormone agonist (GnRH-a) for diagnosis of and therapy for endometriosis. STUDY DESIGN: Multicenter, placebo-controlled clinical tri…

OBJECTIVE: To evaluate the coping resource of social support for women with endometriosis. STUDY DESIGN: The social support experience of 46 women who participate in an endometriosis support group on the internet were examined. A questionn…

BACKGROUND: Laparoscopic neosalpingostomies can be time consuming, costly and technically difficult, resulting in suboptimal results in inexperienced hands. Extracorporeal techniques for pelvic and abdominal organs have already been previou…

BACKGROUND: The Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome occurs in 1 of every 4,000-5,000 female births. It is characterized by normal external genitalia, an absent vagina, absent or rudimentary uterus, and normal fallopian tubes and …

BACKGROUND: Noncommunicating uterine horns are rare, occasionally presenting with functional endometrial cavities. Surgical removal of the noncommunicating horn is commonly performed to prevent endometriosis in these patients. CASE: A 41-y…

BACKGROUND: Endometriosis is a common gynecologic disease that usually presents with pelvic pain and infertility in the reproductive years. It can be complicated by bleeding, such as hematuria or hemoptysis; however, acute massive hemoperit…

OBJECTIVE: To evaluate the efficacy of mifepristone, a potent antagonist of progesterone and glucorticoids, in the management of cancer and disorders related to reproduction. STUDY DESIGN: Reports describing clinical trials of mifepristone…

OBJECTIVE: To review the development of the American Society for Reproductive Medicine (ASRM) classification forms for endometriosis and assess efforts to validate their clinical utility. STUDY DESIGN: The relevant medical literature was r…

OBJECTIVE: To draw attention to the structural features of adhesions associated with pelvic endometriosis since they are less well studied than endometriosis proper. STUDY DESIGN: Sixty-two samples of periovarian adhesions were laparoscopi…

Endometriosis, a benign gynecologic disorder, occurs in about 10% of women of reproductive age and in up to 50% of women with infertility. Endometriosis is defined as the presence of endometrial glandular and stromal cells outside their nor…

Our knowledge of the relationship between minimal to mild endometriosis and subfertility is limited. The main reason for this lack of progress is most probably that the mechanism of subfertility remains to be determined. It has been claimed…