Monoclonal estrogen receptor (ER) antibody and indirect immunoperoxidase techniques were used to study the immunohistochemical localization of ER in paraffin sections of 20 surgical specimens containing foci of endometriosis. The eutopic en…
A comparative histochemical study was performed on endometriotic tissue and uterine endometrium obtained simultaneously from the same patient. No difference in the amount and distribution of glycogen and acid and neutral polysaccharides was…
In 20 infertile patients, the laparoscopic, histologic, and ultrastructural characteristics of endometriotic implants were studied before and after a 2-month course of therapy using 1.25 mg of the antiprogesterone steroid ethylnorgestrienon…
Fourteen cases of mixed müllerian tumour (MMT) of the endometrium, six stromal sarcomas, five uterine leiomyosarcomas, and five leiomyomas were examined, using an immunoperoxidase technique, for the presence of alpha-1-antitrypsin (A1AT), a…
The clinical records and pathologic specimens from 150 patients with endometrial carcinoma were reviewed to test the hypothesis that constitutionally predisposed patients with evidence of endogenous hyperestrinism (i.e., obesity, hypertensi…
Cellular localization of amylase in various ovarian tumors was studied by the immunoperoxidase method using an antibody to human pancreatic amylase. Amylase was present in eight of 34 serous carcinomas and eight of 27 endometrioid carcinoma…
Nine cases of multiple focal extraovarian serous carcinoma were studied, and their gross, light microscopic, and ultrastructural features were compared with those of three serous ovarian tumors and three malignant mesotheliomas. On light mi…
A comparative study on the histological appearance of endometrium and endometriotic tissue obtained simultaneously has been performed. In all, 47 endometriotic samples from 28 patients were examined. In 15 cases, samples from more than one …
The incidence of tubal inflammatory disease in women with endometriosis who had undergone surgery was compared with that in women who had undergone similar operative procedures but who did not have endometriosis and with that in a group of …
The morphologic features of 15 uterine plexiform tumorlets are described. Four of the 15 were examined ultrastructurally; all of these showed features of smooth muscle differentiation. Thus, origin from smooth muscle cells is most likely.
Clinical and pathological features of 41 homologous uterine stromal tumors classified by the criteria of Norris and Taylor were reviewed. These included stromal nodules (12 cases), endolymphatic stromal myosis (20 cases), and stromal sarcom…
Three cases of papillary serous carcinoma of the endometrium ( PSCE ) have been studied by transmission electron microscopy, and the ultrastructural findings compared with those in classical "endometrioid" carcinoma of the endometrium ( CEC…
Longitudinal serial and serial step sections of fallopian tubes from more than 100 patients, subsequent to tubal sterilization procedures, were examined. Thirteen of these patients had pregnancies following their sterilizations. The histolo…
A study of the immunoglobulin content of endometria from women with and without endometriosis has shown that, in women with endometriosis, both IgG and IgA are more commonly found in the interstitium of the endometrial stroma than is the ca…
The cellular DNA content of 50 ovarian common epithelial carcinomas was determined by flow cytometry, and tumours were classified as being either diploid or aneuploid. A significant association between tumour stage and ploidy was demonstrat…
The uterine cervices of 58 patients with cervical adenocarcinoma (seven in situ, 16 microinvasive, and 35 frank invasive) were studied along with 210 cervices that did not show any disease. Squamous metaplasia was confirmed in surface and c…
An immunoperoxidase study, using the Avidin-Biotin-Peroxidase complex method and the monoclonal antibodies, anti-carcinoembryonic antigen (CEA) and anti-carbohydrate determinant 19-9 (CA 19-9), was carried out on 108 common epithelial tumor…
The capacity for indole- or catecholamine precursor uptake and decarboxylation of the argyrophil cell adenocarcinoma of the endometrium was examined by fluorescence microscopy, microspectrofluorometry, and biochemical analyses. Both argyrop…
The emergence in recent years of new concepts and entities pertaining to ovarian endometrioid neoplasia has led to a reappraisal of the subject. In this reappraisal, the double listing of benign endometrioid lesions as both "tumors" and "tu…
We report a population-based histopathologic review of primary ovarian neoplasms. No significant changes in incidence were encountered between the 1969 and 1979 review periods. The most frequent single tumor was benign cystic teratoma (26.5…
Sixteen cases of serous surface papillary carcinoma of the ovary are analyzed. The patients were 45 to 75 years of age. The most common presenting symptoms were malaise, weight loss, and abdominal enlargement. Ascites was a common finding o…