Immunohistochemical study of amylase in common epithelial tumors of the ovary

Ueda G, G Ueda, Yamasaki M, M Yamasaki, Inoue M, M. Inoue, Tanaka Y, Y Tanaka, Abe Y, Y. Abe, Ogawa M, M Ogawa
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists · 1985 · doi:10.1097/00004347-198509000-00008 · PMID:2414239
other OA: closed public-domain-us
Full text JSON View on PubMed View at publisher
⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-08 ⓘ

Amylase was detected in serous and endometrioid ovarian carcinomas but absent in benign, borderline, mucinous, and clear cell tumors, suggesting its potential as a marker.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

⚙ AI-generated deep summary by qwen3.7-flash, 2026-08-24 · read from full text ⓘ

This study utilized immunoperoxidase methods to localize human pancreatic amylase within various common epithelial ovarian tumors. Researchers found that amylase was present in a subset of serous and endometrioid carcinomas, particularly those with poor differentiation, but was absent in benign, borderline, mucinous, and clear cell tumors. The authors concluded that detecting amylase could serve as a useful marker for monitoring specific types of ovarian cancer. Relevance to endometriosis: listed as one indication for GnRH antagonists, though the paper's main focus is uterine fibroids.

Read from the paper's body, not the abstract. Not a substitute for reading the paper. No clinical advice. How this works

Abstract

Cellular localization of amylase in various ovarian tumors was studied by the immunoperoxidase method using an antibody to human pancreatic amylase. Amylase was present in eight of 34 serous carcinomas and eight of 27 endometrioid carcinomas. However, only in one poorly differentiated serous carcinoma and two well-differentiated endometrioid carcinomas were a large number of amylase-reactive cells found. Five benign and three borderline serous tumors contained no amylase. Also, amylase was not detected in any of 34 mucinous tumors or five malignant clear cell tumors. The results obtained suggest that amylase will be a useful tumor marker, when present, for follow-up of endometrioid and serous carcinomas of the ovary.
Full text 1,082 characters · extracted from oa-doi-fallback · click to expand
Original Article: PDF Only Immunohistochemical Study of Amylase in Common Epithelial Tumors of the Ovary - Gaiko Ueda - Masato Yamasaki - Masaki Inoue - Yoshiaki Tanaka - Yoshihito Abe - Michio Ogawa International Journal of Gynecological Pathology 4(3):p 240-244, September 1985. Summary Cellular localization of amylase in various ovarian tumors was studied by the immunoperoxidase method using an antibody to human pancreatic amylase. Amylase was present in eight of 34 serous carcinomas and eight of 27 endometrioid carcinomas. However, only in one poorly differentiated serous carcinoma and two well-differentiated endometrioid carcinomas were a large number of amylase-reactive cells found. Five benign and three borderline serous tumors contained no amylase. Also, amylase was not detected in any of 34 mucinous tumors or five malignant clear cell tumors. The results obtained suggest that amylase will be a useful tumor marker, when present, for follow-up of endometrioid and serous carcinomas of the ovary. Copyright ©1985International Society of Gynecological Pathologists

Text is read by the "Ask this paper" AI Q&A widget below. Extraction quality varies by source — PMC NXML preserves structure cleanly, OA-HTML may include some navigation residue, and OA-PDF can have broken hyphenation. The publisher copy (via DOI) is the canonical version.

My notes (saved in your browser only)

⚙ Ask this paper AI returns verbatim quotes from the full text · source: oa-doi-fallback ⓘ

Answers must be backed by verbatim quotes from this paper's full text. Hallucinated quotes are dropped automatically; if no verbatim passage answers the question, we say so. How this works

Condition tags

endometriosis

MeSH descriptors

Amylases Carcinoma Ovarian Neoplasms Adenocarcinoma Adenocarcinoma Amylases Carcinoma Endometriosis Endometriosis Female Humans Ovarian Neoplasms

Citation neighborhood (no data yet)

We don't have any in-corpus citations linked to this paper yet. The paper's references may be in our DB but unresolved to ``paper_id`` (resolution happens at ingest when the cited DOI matches a row we already have). Run the cross-source citation reconcile pass to retry.

Source provenance

europepmc
last seen: 2026-09-27T09:11:36.575535+00:00
pubmed
last seen: 2026-05-13T22:09:50.790931+00:00
unpaywall
last seen: 2026-10-02T06:31:42.897446+00:00
License: public-domain-us · commercial use OK · attribution required
Courtesy of the U.S. National Library of Medicine