Koichi Hiraki
No ORCID on file
· 28 papers in corpus
· active 2005-2024
Study types
- article 22
- other 3
- review 3
Condition tags
- endometriosis 25
- endometrioma 6
- infertility 5
- chronic_pelvic_pain 4
- adenomyosis 4
- mesh:D004716 1
Top journals
Frequent coauthors
- Akira Fujishita 28
- Khaleque Newaz Khan 26
- Michio Kitajima 25
- Hideaki Masuzaki 24
- Fujishita A 18
- Hiraki K 18
- Kitajima M 17
- Khan KN 16
- Masuzaki H 16
- Tadayuki Ishimaru 14
other
2024
AIM: We investigated the association between the length of anogenital distance (AGD) and intra-vaginal pH, an indicator of vaginal eubiosis or dysbiosis, in women with endometriosis. METHODS: A prospective cohort study was performed includ…
review
2018
BACKGROUND: Endometriosis is a multifactorial disease that mainly affects women of reproductive age. The exact pathogenesis of this disease is still debatable. The role of bacterial endotoxin (lipopolysaccharide, LPS) and Toll-like receptor…
article
2018
We report three cases of women with inguinal endometriosis who were treated with conventional extracorporeal excision and laparoscopy. Case 1: A 38-year-old woman complained of a painful nodule in the left inguinal region. Magnetic resonanc…
article
2018
Objective: We investigated the clinical characteristics of patients with ruptured ovarian endometrioma and examined the role of serum D-dimer levels in ruptured and unruptured ovarian endometrioma.
article
2016
article
2015
ObjectiveA prominent stress reaction in the pelvis of women with endometriosis and the role of human heat shock protein 70 (HSP70) in inflammation and the growth of endometriosis has been recently demonstrated. We report here expression of …
article
2015
other
2015
Adenomyosis is commonly believed to arise from the basalis endometrium. As an estromedin growth factor, hepatocyte growth factor (HGF) exhibits multiple functions in endometriosis, a disease commonly believed to arise from the functionalis …
article
2014
article
2014
ObjectivesHuman heat shock protein 70 (HSP70) has been reported to enhance Toll-like receptor 4-mediated pelvic inflammation and growth of endometriotic cells. However, information on tissue expression of HSP70 before and after treatment wi…
article
2014
STUDY QUESTION: Is there any risk of intra-uterine bacterial colonization and concurrent occurrence of endometritis in women with endometriosis? SUMMARY ANSWER: An increase in intra-uterine microbial colonization and concurrent endometritis…
article
2014
Endometriosis is a multifactorial disease mostly affecting women of reproductive age and is associated with chronic pelvic pain and infertility. Even after 300 years, most of the literature claims that pathogenesis and/or pathophysiology of…
article
2013
STUDY QUESTION: Is there any occurrence of hidden (occult) endometriotic lesions in normal peritoneum of women with and without visible endometriosis? SUMMARY ANSWER: We detected a slightly higher occurrence of occult microscopic endometrio…
article
2012
STUDY QUESTION: Is the occurrence of pelvic pain in women with ovarian endometrioma associated with coexisting peritoneal lesions (PLs)? SUMMARY ANSWER: Pelvic pain in women with ovarian endometrioma is usually associated with coexisting PL…
article
2011
We measured serum anti-Müllerian hormone levels before and after surgery in women undergoing unilateral and monolocular cystectomy for benign ovarian diseases. Comparing to control benign cysts, we found a significant decline in serum anti-…
article
2010
BACKGROUND: We recently demonstrated the effect of gonadotrophin-releasing hormone agonist (GnRHa) on tissue inflammation, angiogenesis and apoptosis in endometriosis, adenomyosis and uterine myoma. Here, we investigated expression of GnRH …
article
2010
article
2010
ObjectivesWe investigated the effect of human seminal fluid on the growth of endometrial cells derived from women with and without endometriosis.Study designSeminal plasma (SP) was collected from 18 healthy fertile men. Serum, peritoneal fl…
article
2010
Escherichia coli contamination of menstrual blood and effect of bacterial endotoxin on endometriosis
To test the hypothesis that bacterial contamination of menstrual blood could be a local biologic event in the development of endometriosis, menstrual blood was cultured and bacterial endotoxin was measured in menstrual blood and peritoneal …
article
2009
BACKGROUND: Information is limited regarding the multifunctional role of GnRH agonist (GnRHa) therapy in reproductive diseases. We investigated the pattern of changes in inflammatory reaction, micro-vessel density and apoptosis in the tissu…
review
2009
Macrophages, dendritic cells, and Toll-like receptors (TLRs) are integral components of the innate immune system. This rapidly reactive system responds immediately to infectious or other non-self agents, thereby inducing an inflammatory res…
article
2008
Endometriosis, a chronic disease characterized by endometrial tissue located outside of the uterine cavity and is associated with chronic pelvic pain and infertility. However, an in-depth understanding of the pathophysiology of endometriosi…
review
2008
Endometriosis, a chronic disease characterized by endometrial tissue located outside the uterine cavity is associated with chronic pelvic pain and infertility. However, an in-depth understanding of the pathophysiology of endometriosis is st…
article
2008
BACKGROUND: We investigated the role of human heat-shock protein 70 (Hsp70) in Toll-like receptor 4 (TLR4)-mediated growth of endometriosis. METHODS: TLR4 expression was examined in macrophages (M) isolated in primary culture from the perit…
article
2006
BACKGROUND: The association between uterine myoma and infertility is still controversial. The anatomical defect of endometrium by uterine fibroids could be a factor for reducing pregnancy rates and increasing miscarriage rates. However, pre…