Thomas M D'Hooghe

No ORCID on file · 64 papers in corpus · active 2002-2026

Study types

  • article 34
  • review 20
  • other 5
  • letter 4
  • rct 1

Condition tags

  • endometriosis 62
  • infertility 8
  • chronic_pelvic_pain 1
  • endometrioma 1
  • die_deep_infiltrating 1
review 2012
Current opinion in obstetrics & gynecology ·doi:10.1097/gco.0b013e3283556285

PURPOSE OF REVIEW: To present the clinical outcome after laparoscopic radical excision of deeply infiltrative endometriosis (DIE) with colorectal extension and laparoscopic segmental bowel resection. RECENT FINDINGS: In three different stud…

other 2011
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719110380277

The attitude of patients with reproductive disorders regarding the use of nonhuman primates (NHPs) in preclinical reproductive research and its determinants was examined. A survey was conducted on 299 patients with fertility problems and/or…

article 2011
Reproductive biology and endocrinology : RB&E ·doi:10.1186/1477-7827-9-113

BACKGROUND: Endometriosis is associated with chronic subclinical inflammation. C-reactive protein (CRP), a marker of inflammation, could serve as a biomarker of endometriosis. We tested the hypothesis that a high sensitivity CRP assay (hsCR…

article 2011
Implementation science : IS ·doi:10.1186/1748-5908-6-7

BACKGROUND: Clinical guidelines are intended to improve healthcare. However, even if guidelines are excellent, their implementation is not assured. In subfertility care, the European Society of Human Reproduction and Embryology (ESHRE) guid…

article 2010
Fertility and sterility ·doi:10.1016/j.fertnstert.2010.07.1060
article 2010
Fertility and sterility ·doi:10.1016/j.fertnstert.2010.06.084
article 2010
Reproductive biomedicine online ·doi:10.1016/j.rbmo.2010.01.018
article 2010
Reproductive biomedicine online ·doi:10.1016/j.rbmo.2010.04.023
article 2010
Reproductive biology and endocrinology : RB&E ·doi:10.1186/1477-7827-8-123

BACKGROUND: According to mRNA microarray, proteomics and other studies, biological abnormalities of eutopic endometrium (EM) are involved in the pathogenesis of endometriosis, but the relationship between mRNA and protein expression in EM i…

review 2009
Human Reproduction ·doi:10.1093/humrep/dep045

In response to the pressing need for more efficacious and safer therapeutics for endometriosis, there have been numerous reports in the last decade of positive results from animal and in vitro studies of various compounds as potential thera…

other 2009
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719108330568

Endometriosis is an estrogen-dependent disorder where endometrial tissue forms lesions outside the uterus. Endometriosis affects an estimated 10% of women in the reproductive-age group, rising to 30% to 50% in patients with infertility and/…

review 2009
Molecular human reproduction ·doi:10.1093/molehr/gap075

A 1993 study reporting the link between exposure to dioxin and the risk of developing endometriosis in rhesus monkeys prompted many investigators to look suspiciously at dioxin. Since 1993, many in vitro, animal and epidemiological studies …

review 2009
Frontiers in bioscience (Elite edition) ·doi:10.2741/e40

A clear picture of the dynamic relationship between the endometrium and peritoneum is emerging as both tissues may participate in the spontaneous development of endometriosis. Various adhesion molecules, pro-inflammatory cytokines and chemo…

article 2007
Women's health (London, England) ·doi:10.2217/17455057.3.5.637

Endometriosis is a benign, estrogen-dependent disease and is now recognized as an enigmatic disease owing to its various clinical manifestations and locations. The lack of a reliable and specific method for the early detection of endometrio…

article 2007
Fertility and sterility ·doi:10.1016/j.fertnstert.2006.11.205
article 2007
Fertility and sterility ·doi:10.1016/j.fertnstert.2007.05.062
article 2007
Fertility and sterility ·doi:10.1016/j.fertnstert.2007.02.057
article 2007
Women's health (London, England) ·doi:10.2217/17455057.3.5.629

Endometriosis is a gynecological disorder characterized by the growth of endometrial tissue outside the uterine cavity. Although the prevalence of endometriosis is well documented in women living in developed countries, studies on the preva…

article 2007
Women's health (London, England) ·doi:10.2217/17455057.3.5.647

In women of reproductive age, health economic costs are estimated to be considerably higher for endometriosis than for conditions such as Crohn's disease, migraine and hypertension, and similar to the cost of diabetes. However, more awarene…

article 2007
Women's health (London, England) ·doi:10.2217/17455057.3.5.617

Endometriosis is an estrogen-dependent disease and estrogen-related pathways are imbalanced in women with endometriosis. One of the key enzymes in estrogen synthesis is aromatase. Inhibiting this pathway at several points is a promising ide…

article 2007
Women's health (London, England) ·doi:10.2217/17455057.3.5.615

10.2217/17455057.3.5.615 © part of Short biography Thomas D’Hooghe Clinical Head, Leuven University Fertility Center; Chair, European Society for Human Reproduction and Embryology Special Interest Group for Endometriosis; Editor-in-Chief, G…

review 2007
Gynecologic and obstetric investigation ·doi:10.1159/000101739

The process of embryo implantation includes attachment of the embryo to the endometrium and penetration through the epithelial layer, decidualization of the basement membrane, invasion of the uterine stroma and access to blood supply. This …

review 2006
Expert opinion on emerging drugs ·doi:10.1517/14728214.11.3.503

Endometriosis is a common, estrogen-dependent, gynaecological disease, defined as the presence of endometrial-like tissue outside the uterus. Although several medications are used for treatment of the disease, they are associated with high …

review 2006
Current opinion in obstetrics & gynecology ·doi:10.1097/01.gco.0000233929.27145.f3

PURPOSE OF REVIEW: The aim of this review paper is to discuss the relationship between endometriosis and assisted reproductive technology. More specifically, the following clinically relevant issues will be discussed. (1) Does the presence …

article 2006
Fertility and sterility ·doi:10.1016/j.fertnstert.2005.11.060