Charles Chapron

No ORCID on file · 365 papers in corpus · active 1990-2026

Study types

  • article 240
  • review 54
  • other 40
  • book-chapter 18
  • letter 7

Condition tags

  • endometriosis 297
  • die_deep_infiltrating 76
  • infertility 67
  • endometrioma 49
  • adenomyosis 41
  • dysmenorrhea 36
  • chronic_pelvic_pain 33
  • dyspareunia 25
  • bladder_endometriosis 12
  • bowel_endometriosis 2
review 2012
Fertility and sterility ·doi:10.1016/j.fertnstert.2012.04.051

Endometriosis is a chronic inflammatory disease affecting women's health. Pain and infertility are the major symptoms caused by a hormonal/immunological dysfunction, which causes an endometrial impairment. The same pathogenetic mechanisms a…

article 2012
·doi:10.1016/j.jmig.2012.08.052
review 2012
Presse medicale (Paris, France : 1983) ·doi:10.1016/j.lpm.2011.07.017

Endometriosis affects 6 to 10 % of all women of childbearing age. Intestinal involvement is defined by muscularis infiltration and has been estimated to occur in 8 % to 12 % of women with endometriosis. The most common sites are rectum, sig…

article 2012
Human Reproduction ·doi:10.1093/humrep/des274

STUDY QUESTION: Are anti-Müllerian hormone (AMH) levels lower in women with endometriosis, notably those with endometriomas (OMAs) and deep infiltrating lesions, compared with controls without endometriosis? SUMMARY ANSWER: Endometriosis an…

article 2012
·doi:10.1016/j.jmig.2012.08.157
other 2012
Expert opinion on emerging drugs ·doi:10.1517/14728214.2012.668885

Introduction: Endometriosis, histologically defined as the presence of endometrium-like tissue - glands and stroma - that develops outside of the uterine cavity, is still an enigmatic disease responsible for pelvic pain and infertility. The…

article 2012
Journal of reproductive immunology ·doi:10.1016/j.jri.2012.06.001

Cytokines, and specifically interleukin 6 (IL-6) and interleukin 8 (IL-8), have been associated with the pathogenesis of endometriosis. We studied serum concentrations of IL-6 and IL-8 in patients with deep infiltrating endometriosis (DIE) …

article 2012
Human Reproduction ·doi:10.1093/humrep/der462

BACKGROUND: The objective of this study was to evaluate the significance of severe preoperative pain for patients presenting with ovarian endometrioma (OMA). METHODS: Three hundred consecutive patients with histologically proven OMA were en…

article 2012
·doi:10.1016/j.jmig.2012.08.029
review 2012
Journal de gynecologie, obstetrique et biologie de la reproduction ·doi:10.1016/j.jgyn.2012.11.009

Recurrence of deep endometriosis remains a major issue in the management of endometriosis. The main cause for recurrence appears to be an incomplete excisional surgery. Therefore, the goal of the primary surgery should be the complete resec…

article 2012
Human Reproduction ·doi:10.1093/humrep/des154

BACKGROUND: Interleukin 33 (IL-33) is a cytokine involved in fibrotic disorders. We have analyzed IL-33 levels in the sera and peritoneal fluids of women with various forms of endometriosis and investigated the correlation with disease acti…

article 2012
Fertility and sterility ·doi:10.1016/j.fertnstert.2011.12.051

ObjectiveTo investigate key genes expression of the sphingosine-1-phosphate pathway in endometriotic tissues.DesignA case-control laboratory study.SettingTertiary care university hospital.Patient(s)A total of 31 women, with (n = 16) and wit…

article 2012
·doi:10.5301/je.2012.9918
article 2011
·doi:10.1016/j.jmig.2011.08.499
article 2011
·doi:10.1016/j.jmig.2011.08.064
article 2011
Human Reproduction ·doi:10.1093/humrep/der346

BACKGROUND: An inverse association between BMI and endometriosis has been reported but remains controversial. We decided to evaluate the association between BMI and the different types of endometriosis, classified as superficial endometrios…

book-chapter 2011
·doi:10.1007/978-2-8178-0061-5_27
article 2011
·doi:10.1016/j.jmig.2011.08.066
review 2011
Journal of pediatric and adolescent gynecology ·doi:10.1016/j.jpag.2011.07.006

Endometriosis, a disease of young females that is possibly a devastating ailment requiring surgery, appears to be associated with certain features encountered in adolescence. First among these symptoms is the history of severe and lasting d…

article 2011
Human Reproduction ·doi:10.1093/humrep/der156

BACKGROUND: The relationship between the use of oral contraception (OC) and endometriosis remains controversial. We therefore compared various characteristics of OC use and the surgical diagnosis of endometriosis histologically graded as su…

article 2011
·doi:10.1016/j.jmig.2011.08.254
article 2011
·doi:10.1093/humrep/26.s1.35
article 2011
The American journal of pathology ·doi:10.1016/j.ajpath.2011.04.020

Deep infiltrating endometriosis (DIE) is a particular clinical and histological entity of endometriosis responsible for chronic pelvic pain and infertility. Here we characterize the proliferative phenotype of DIE cells, to explore the cellu…

article 2011
Fertility and sterility ·doi:10.1016/j.fertnstert.2011.01.131

Steroidogenic factor-1 (SF-1) protein expression was not observed in any form of endometriosis (peritoneal, ovarian, or deep infiltrating endometriosis), which suggests that SF-1 locally produced by endometrial or stromal cells may not play…

article 2010
Fertility and sterility ·doi:10.1016/j.fertnstert.2009.09.031

ObjectiveTo investigate the effects of antiproliferative drugs (anastrozole, methotrexate, and 5-fluorouracil [5-FU]) on the proliferation of endometriotic cells in vitro and in vivo.DesignEx vivo study on human endometrial and endometrioti…