Maria I. Yarmolinskaya

BACKGROUND: There are currently no uniform standards for adenomyosis diagnosis, so the search for the most informative methods is an urgent task. This article presents modern views on the diagnosis of adenomyosis and the role of ultrasound …

Background. Endometriosis is a chronic progressive recurrent disease associated with pelvis pain, menses disorders and infertility. The prevalence of endometriosis (EGE) tends to increase steadily and reaches 15% among women of reproductive…

The article presents the results of the investigation of cytokine production by endometrioid heterotopias in organotypic cultivation in comparison with the cell secretory activity of peritoneal fluid and endometrial tissue in women with ext…

BACKGROUND: Genital endometriosis is one of the most pressing problems of modern gynecology. Melatonin is a promising drug with a potentially curative effect on endometriosis. AIM: The aim of this study was to conduct a comparative analysis…

Study Objective: To assess clinical efficiency of combination therapy with Metformin and Metformin monotherapy in the management of endometriosis genitalis externa (EGE). Study Design: perspective randomised singe-arm study in parallel grou…

Эндометриоз — это хроническое, рецидивирующее заболевание, характеризующееся синдромом хронической тазовой боли и бесплодием, что существенно снижает качество жизни больных. Несмотря на высокую эффективность хирургического лечения, удалени…

OBJECTIVE: To compare the effectiveness of two different treatment regimens of dydrogesterone in the management of endometriosis-related chronic pelvic pain. DESIGN: Observational, prospective cohort study over six months. SETTING: Twenty…

Эндометриоз — это заболевание, характеризующееся иммунной дисфункцией на различных уровнях: от нарушений в передаче сигналов цитокинами к изменениям в популяциях клеток иммунной системы, в результате чего развивается персистирующая воспали…

BACKGROUND: The high prevalence, the lack of reliable data on the etiology, as well as the complexity of diagnosis and treatment of genital endometriosis indicate the urgency of the problem. AIM: The aim of this study was to analyze and sum…

BACKGROUND: Growth factors play an important role in the pathogenesis of genital endometriosis. Insulin and insulin-like growth factors are involved in mitosis and differentiation in the endometrium during the menstrual cycle and early preg…

The prevalence of genital endometriosis and adenomyosis, in particular, is tending to increase. The lack of a complete understanding of the pathogenetic mechanisms and multifactorial causes of adenomyosis, the low effectiveness of existing …

BACKGROUND: Uterine leiomyoma and endometriosis are the most common gynecological diseases in women of reproductive age. A number of data indicate that there are common elements in the pathogenesis of these hyperproliferative conditions. Th…

Administration of menopausal hormone therapy (MHT) in patients with genital endometriosis (GE) is a controversial issue requiring a patient-personalized approach. Current principles for MHT selection and prescription in patients with anamne…

BACKGROUND: Retinol in its various forms, being a powerful antioxidant, has a multifaceted effect on the functioning of body systems. Replenishment of the daily requirement for the vitamin is possible only when it is supplied from outside s…

AIM: The aim of this study was to analyze the association between the vitamin D receptor gene polymorphism and the risk of developing genital endometriosis and type 1 diabetes mellitus. MATERIALS AND METHODS: The frequency of allelic varian…

UNLABELLED: Genital endometriosis (GE) is a widespread multifactorial disease thus making it necessary to carry on studying its pathogeny in order to work out target therapy techniques. Studying vitamin D role in GE pathogeny is a new promi…

This article summarizes data on the prevalence, risk factors and the role of external genital endometriosis in the development of ectopic pregnancy. The existing algorithms for the use of conservative therapy of ectopic pregnancy of rare lo…

Relevance.Deep infiltrative endometriosis (DIE) is a particular form of endometriosis with a more severe symptoms and dysfunction of the neighboring organs. Inspite of the fact that in recent years, much had been done to understand the path…

OBJECTIVE: The present study was to find a pathogenic evidence for dopamine agonist application in patients with endometriosis associated pain syndrome. PATIENTS AND TECHNIQUE: The study involved 227 patients of reproductive age with histo…

Hypothesis/aims of study. Endometriosis is a multifactorial, chronic and recurring condition that has a multifaceted negative impact on womens fertility. The aim of the study was to assess the effect of genital endometriosis on the female r…

Endometriosis is a widespread disorder in which a tissue morphologically and physiologically similar to endometrium is observed outside the uterine cavity. Earlier, we identified a number of genes that are overexpressed in ectopic endometri…

В статье обобщены современные данные о применении у больных с генитальным эндометриозом гормональных контрацептивов: комбинированных эстроген-гестагенных препаратов, в том числе имеющих в своем составе эстрогены, биоидентичные натуральным;…