Yi Zhang

OBJECTIVE: in adenomyosis tissues, and to explore their roles in the incidence and development of adenomyosis-induced dysmenorrhea. METHODS: was measured. RESULTS: = 0.007). CONCLUSION: which is proportional to the degree of pain.

tRNA-derived fragments are dysregulated and could be involved in the pathogenesis and progression of ovarian endometriosis.

AIM: Circular RNAs (circRNAs) with miRNA response elements (MREs) could function as competing endogenous RNA (ceRNA) in regulating gene expression. This study was carried out to identify the expression profile and role of circRNAs in endome…

The present study aimed to detect the expression of somatostatin (SS) and SS receptor (SSTR)1-5 in tissues from patients with endometriosis (EMS). Reverse transcription-quantitative polymerase chain reaction analysis was applied to examine …

OBJECTIVE: To investigate the expressions of miR23b and Sp1 in ovarian endometriosis and their clinic significance. Methods: qPCR was used to detect the expression of miR23b and Sp1 mRNA in paired ectopic/eutopic and normal endometrium. Imm…

In this study, we investigated the expression of interleukin 35 (IL-35) and its receptors in endometriosis, analyzed the function of IL-35 in primary culture model of endometrial stromal cells (ESCs), and evaluated their clinicapathological…

OBJECTIVE: To study the clinical features of gynecological diseases in hospitalized children. METHODS: A retrospective analysis was performed for the clinical data of 147 children with gynecological diseases who were hospitalized and treate…

Objective To observe the clinical effect of letrozole combined with metformin on endometriosis. Methods One hundred and twelve cases of endometriosis from October 2013 to November 2014 were randomly divided into control group and tre…

STUDY OBJECTIVE: To evaluate the safety and efficacy of a new crosslinked hyaluronan (NCH) gel in reducing postoperative adhesions. DESIGN: Randomized controlled trial (Canadian Task Force classification I). SETTINGS: Seven departments of…

OBJECTIVE: To examine the expression of G protein-coupled estrogen receptor (GPER) and Gankyrin in ovarian endometriosis (OEM) and to evaluate its clinicopathological significance. METHODS: Immunohistochemistry was conducted to determine th…

ObjectiveThe aim of this study was to examine the expression of G protein-coupled estrogen receptor (GPER) and Gankyrin in ovarian endometriosis, analyze their clinicopathological significance, and investigate their correlation.MethodsQuant…

OBJECTIVE: To explore the advantage, feasibility and safety of modified approach to difficult vaginal hysterectomy and provide scientific rationales for expanding its indications. METHODS: A retrospective study was conducted for 237 patient…

OBJECTIVE: To compare the clinical effect of Chinese medicine (CM) and Western medicine (WM) for controlling the recurrence of pelvic endometriosis after a conservative operation. METHODS: The study was a multi-center, randomized, parallel…

OBJECTIVE: The purpose of this study is to investigate the potential genetic alterations at DNA level in patients with ovarian endometriosis by high-resolution array-based comparative genomic hybridization (array-CGH) analysis. METHODS: Fol…

Objective:To explore the application value of transvaginal hydrolaparoscopy(THL) in diagnosis of infertility.Methods:150 infertile cases who had visited outpatient department of the institute from May 2009 to October 2010 were selected,then…

Interleukin-16 (IL-16), a proinflammatory cytokine, plays a pivotal role in inflammatory diseases as well as in the pathogenesis of endometriosis. The aim of this study was to evaluate the association of IL-16 gene polymorphisms with the ri…

Objective:To investigate the single nucleotide polymorphisms of macrophage migration inhibitory factors(MIF)-173 in the endometriosis(EMs) and non-endometriosis(non-Ems) patients,also explore the association of MIF-173(G/C) and the suscepti…

【Objective】To investigate the surgical technique and analyse clinical outcome of laparoscopic clinical operation to cure ovarian endometriomas. 【Methods】The clinical data of 488 cases of ovarian endometriomas underwent laparoscopic operatio…

Objective To investigate the expression of 5-lipoxygenase (5-LOX) in endometriosis and analyze the relationship of 5-LOX and angionesis in endometriosis. Methods Immunochemical method was used to determine the expression of 5-LOX, VEGF, and…

Endometriosis is the presence of endometrial glands and stroma outside the endometrial cavity and is the most common known cause of pelvic pain．The number of women being diagnosed with the disease is increasing，afflicting about 7-10％of wome…

Objective To explore the role of TGF-βand TGIF in the pathogenesis of endometriosis. Methods The expression of TGF-β and TGIF was detected by immunohistochemistry method in the ectopic and eutopic endometrium of 30 cases with endometriosis …

OBJECTIVE: To investigate the clinical efficacy of Tiaomian Huayu Decoction (THD) in treating patients with endometriosis. METHODS: Patients in the treated group were administered with THD, those in the control group were given provera. T-c…

ObjectiveThe objective was to investigate the expression of heparanase (Hpa) and angiopoietin-2 (Ang-2) in endometriosis.Study designIn ectopic and eutopic endometrium of patients undergoing laparoscopy for endometriosis (n=86) and in norma…

OBJECTIVE: To investigate the relationship between heparanase (Hpa) and angiopoietin-2 (Ang-2) gene expression and the development of endometriosis (EM). METHODS: Expression of Hpa gene and Ang-2 mRNA in the eutopic and ectopic endometrium…