Zhang H

Ovarian cancer, particularly epithelial ovarian cancer (EOC), is the most aggressive and lethal gynecologic malignancy, necessitating the development of innovative and potent therapies to improve its prognosis. Human polo-like kinase 1 (PLK…

BackgroundUterine fibroids present significant obstetric challenges, particularly in late pregnancy. This study compared the outcomes of cesarean section combined with myomectomy (CS+M) versus cesarean section followed by elective myomectom…

OBJECTIVE: To explore the clinical efficacy of commonly used conservative treatments for adenomyosis using both TCM and Western medicine. METHODS: 210 patients with adenomyosis were selected and divided into 3 groups: Group A (Dan'e Fukang…

AimThis study aimed to compare the diagnostic accuracy of ultrasound (US) and magnetic resonance imaging (MRI) in the detection of placenta accreta spectrum (PAS) disorders in a single tertiary care setting.Materials and methodsAll eligible…

[This corrects the article DOI: 10.3389/fgene.2025.1614573.].

Polycystic ovary syndrome (PCOS) is a common reproductive disorder characterized by hyperandrogenism, ovulatory dysfunction, and polycystic ovaries. The quality of oocytes in PCOS patients remains poor, leading to poor pregnancy outcomes. T…

In clinical drug development, two fundamental questions must be addressed: what is the success rate of drugs in clinical trial; how does such rate change over time. Here, a dynamic strategy for calculating clinical trial success rate (ClinS…

BackgroundCurrent advances in high-throughput sequencing technology enable the precise identification of Y chromosome microdeletion and primary duplication in infertile couples, but the mechanism and clinical significance of these mutations…

Endometriosis (EMs) is a chronic gynecologic condition characterized by the growth of endometrial stromal and glandular tissue outside the uterine cavity of unknown etiology. Currently, ferroptosis resistance, increased glycolysis, and incr…

BACKGROUND: Adenomyosis is often associated with abnormal uterine bleeding (AUB), which can lead to anemia. Recurrent bleeding, especially in the presence of cerebral infarction risk, may exacerbate the likelihood of cerebral infarction thr…

Study questionIs there an association between changes in endometrial thickness (EMT) following progesterone administration and pregnancy outcomes in frozen-thawed embryo transfers (FETs) at Day 3 (D3) and blastocyst stages?Summary answerEnd…

Yizheng Zu,1– 4,* Yi Xie,1– 4,* Huale Zhang,1– 4,* Lichun Chen,1– 4 Shihan Yan,1 Zhenna Wang,1 Zhuanji Fang,1– 4 Shunhe Lin,1 Jianying Yan1– 4 1College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical Universi…

PURPOSE: Endometriosis has been hypothesized to increase the risk of preeclampsia (PE) and eclampsia, although the exact mechanism of this relationship is not clear. This study aimed to further explore the potential association between endo…

ObjectiveThis study aims to demonstrate that the EN2 protein in cervical mucus may serve as a novel biomarker for screening endometrial cancer.Materials and methodsThis study included 133 patients who were treated at Beijing Obstetrics and …

Previous epidemiological studies have suggested that green tea catechins, including Epigallocatechin-3-gallate (EGCG), the most abundant polyphenol in green tea, may be associated with reduced serum folate levels. This is of particular inte…

Gastric cancer (GC) is one of the most common malignancies and is a highly heterogeneous disease; it is also a leading cause of cancer-related death. Owing to the complexity and late-stage diagnosis of GC, the prognosis remains poor. To exp…

BACKGROUND: Microplastics (MPs) are pervasive environmental pollutants that pose significant health risks. While their prevalence in ecosystems is well-established, their accumulation in the human body and potential role in tumorigenesis de…

Diseases of the female reproductive system are prevalent. These conditions often have a high proportion of asymptomatic patients and prolonged treatment durations. Estrogen, a crucial steroid hormone, plays a central role in most diseases o…

Ovarian cancer remains a formidable global health burden, characterized by frequent late-stage diagnosis and elevated mortality rates attributable to its elusive pathogenesis and the critical lack of reliable early-detection biomarkers. Eme…

Endometriosis (EM) is a non-cancerous disease that exhibits certain tumor-like properties. While hormonal therapies and surgical excision are standard treatments with proven efficacy in alleviating EM symptoms, they are often accompanied by…

Background: Endometriosis results in dysmenorrhea, dyspareunia, chronic pelvic pain and infertility in reproductive-age women. However, no effective treatment methods have been applied to the disease, and the pathogenesis of endometriosis i…

ObjectiveTo develop a predictive tool in the form of a Nomogram based on the Cox regression model, which incorporates the impact of the length of treatment cycles on the outcome of live birth, to evaluate the probability of infertile couple…

The skeletal muscle is highly susceptible to injury in daily life. Severe skeletal muscle injuries often result in incomplete regeneration, leading to functional impairment. In clinical practice, understanding the extent of skeletal muscle …

Ferroptosis, a recently discovered form of programmed cell death triggered by the excessive accumulation of iron-dependent lipid peroxidation products, plays a critical role in the development of various diseases. However, whether it is inv…