PloS one

OBJECTIVE: To evaluate the behavioral and clinical characteristics of endometriosis patients at the largest tertiary healthcare center in Lebanon and to analyze the effect of endometriosis symptoms, age of menarche, sexual activity, and inf…

OBJECTIVE: This study aimed to investigate the association between body mass index (BMI) and sexual function, measured by the Female Sexual Function Index (FSFI), in women with endometriosis, adjusting for the number of endometriosis sympto…

BACKGROUND: Ferritin may be elevated as an acute-phase reactant in inflammatory conditions, potentially masking iron deficiency. We aimed to evaluate the frequency of iron deficiency and the diagnostic significance of transferrin saturation…

[This corrects the article DOI: 10.1371/journal.pone.0057724.].

A new humoral factor has been detected, within a project aiming to disclose the body's reproductive hormonal brake against tissue overgrowth, micrin ('my-crin'). Factor purification involved fractionation of ovine and bovine ovarian follicu…

OBJECTIVE: This scoping review aimed to map the evidence on how digital health technologies are used for pain management in endometriosis. METHODS: This scoping review adhered to the Joanna Briggs Institute methodological framework and fol…

BACKGROUND: Endometriosis is a complex gynecological condition characterized by endometrial tissue growing outside the uterus. In many in vitro studies, almost all progestins have indicated the anti-proliferation and apoptosis of endometrio…

INTRODUCTION: Endometriosis is a prevalent chronic gynecological condition affecting women of reproductive age, characterized by ectopic endometrial-like tissue growth. Despite its significant impact on quality of life, fertility, and healt…

BACKGROUND: Drug-drug interactions (DDIs) represent a major preventable cause of medication-related harm globally. Their prevalence varies across health systems, but common drivers include polypharmacy, aging populations, and specialty-spec…

INTRODUCTION: The objective of this study was to investigate alleviation of adenomyosis symptoms after microwave ablation (MWA) and uterine artery embolization (UAE) in a small pilot study. MATERIAL AND METHODS: 20 premenopausal women with…

BACKGROUND: A link exists between decorin (DCN) and endometriosis, nevertheless, the role of DCN in this condition remains unclear. This study aims to bioinformatically characterize DCN expression, diagnostic value, and related signaling in…

BACKGROUND: Increased uterine artery resistance in pregnant women with a history of cesarean section has been suggested to contribute to adverse pregnancy outcomes. However, the literature presents conflicting reports on this association. I…

BACKGROUND: Long-acting Gonadotropin-releasing hormone analogs(GnRHa), including leuprolide, goserelin, histrelin, buserelin, triptorelin, have been widely used for a variety of diseases including prostate cancer, breast cancer, endometrios…

BACKGROUND: Spironolactone, a potassium-sparing diuretic, is commonly prescribed for conditions such as heart failure, hypertension, and hyperaldosteronism. This study aims to explore and analyze the safety profile of spironolactone by exam…

The association of lipid accumulation product (LAP) and the likelihood of endometriosis prevalence has not been previously mentioned. The research aimed to assess the possible potential association between LAP and endometriosis in nationwid…

STUDY BACKGROUND: Preoperative assessment of the severity of pelvic adhesions in endometriosis remains challenging. Inflammation may drive adhesion formation, and the predictive value of the neutrophil percentage-to-albumin ratio (NPAR, the…

PURPOSE: Transvaginal ultrasound (TVUS) is pivotal for diagnosing reproductive pathologies in individuals assigned female at birth, often serving as the primary imaging method for gynecologic evaluation. Despite recent advancements in AI-dr…

Adenomyosis and leiomyomas are common benign uterine disorders characterized by abnormal cellular proliferation. The BCL6 protein, a transcriptional repressor implicated in cell proliferation and oncogenesis, has been linked to the pathogen…

BACKGROUND: The surgical management of endometrioma(s) remains challenging. Although laparoscopic surgery is a well-established treatment of endometrioma(s), caution is required to minimize ovarian damage. Several surgical techniques have b…

STUDY OBJECTIVE: To report individual early and long-term functional outcomes of 43 women who underwent double circular stapler technique (DCST) for colorectal deep endometriosis (DE). METHODS: This multidisciplinary observational study was…