Peng Cao

No ORCID on file · 14 papers in corpus · active 2009-2025

Study types

  • article 9
  • other 2

Condition tags

  • endometriosis 8
  • dysmenorrhea 2
  • adenomyosis 2
2025
Nature communications ·doi:10.1038/s41467-025-65847-0

Despite intensive development, P2X7 modulators have struggled in translation due to human genetic variability and species-dependent drug responses. Here, we identify PSFL1191, a portal-of-central-pocket (PCP)-site inhibitor selective for hu…

2024
Nature communications ·doi:10.1038/s41467-024-51815-7

P2X receptors, a subfamily of ligand-gated ion channels activated by extracellular ATP, are implicated in various physiopathological processes, including inflammation, pain perception, and immune and respiratory regulations. Structural dete…

article 2022
Journal of ethnopharmacology ·doi:10.1016/j.jep.2022.115121

Ethnopharmacological relevanceIn the practice of traditional Chinese medicine, endometriosis is believed to be caused by blood stasis and is characterised by dysmenorrhea, which is difficult to control. Shixiao San (SXS) has a long history …

other 2022
Journal of ethnopharmacology ·doi:10.1016/j.jep.2022.115540

ETHNOPHARMACOLOGICAL RELEVANCE: Guizhi Fuling decoction (GZFL decoction) is a famous formula in the Synopsis of the Golden Chamber, which has a long history in treating endometriosis. However, its exact mechanism remains unclear. AIM OF ST…

article 2020
Experimental and therapeutic medicine ·doi:10.3892/etm.2020.8994

, can be traced back to the Song dynasty. Traditionally, SXS has been used to treat irregular menstruation, pelvic pain, progressive dysmenorrhea, and postpartum lochiorrhea. The management of adenomyosis (AM) is challenging and to the best…

2018
·doi:10.20944/preprints201806.0074.v1
article 2016
Journal of ethnopharmacology ·doi:10.1016/j.jep.2016.07.019

Ethnopharmacological relevanceWenshen Xiaozheng Tang (WXT), a traditional Chinese medicine prescription, exerted a good therapeutic effect on endometriosis. However, the underlying mechanism is unclear. In the present study, we sought to ev…

article 2015
·doi:10.3724/sp.j.1008.2015.00006
article 2014
Climacteric : the journal of the International Menopause Society ·doi:10.3109/13697137.2013.876618

OBJECTIVE: The guizhi fuling (GZFL) capsule has been a traditional Chinese medicine for the treatment of gynecological inflammation for the past thousands of years. However, as a formula, its therapeutic mechanism has not been clearly eluci…

other 2014
Fertility and sterility ·doi:10.1016/j.fertnstert.2013.10.050

OBJECTIVE: To investigate the balance between regulatory T cells (Treg) and T-helper 17 cells (T(H)17) in peripheral blood and uteri of women with adenomyosis (AM), and to evaluate their potential correlation with dysmenorrhea and CA-125 le…

article 2013
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719113483008

The objective of this study is to investigate the effect of Wenshen Xiaozheng Tang (WXT) on the development of endometriosis in a rat model. Sprague-Dawley rats in which endometriotic implants were induced were divided randomly into 3 group…

article 2013
Climacteric : the journal of the International Menopause Society ·doi:10.3109/13697137.2013.771331

OBJECTIVE: To evaluate the effect of Wenshen Xiaozhng Tang (WXT) on ectopic endometrial growth and on angiogenesis in endometrial implants in a rat model. METHODS: Sprague-Dawley rats with endometriotic implants were randomly treated with l…

article 2011
Journal of ethnopharmacology ·doi:10.1016/j.jep.2011.01.003

Aim of the studyTo investigate the immunological regulation of Guizhi Fuling Capsule (GZFLC) on rat endometriosis.Materials and methodsTwenty-seven rats, in which endometriotic implants were induced by transplanting autologous uterine tissu…

article 2009

Objective To establish and to compare a rat model of endometriosis of autotransplantation of uterine tissue into three sites of rats.Methods Thirty adult unmating female SD rats were autotransplantated of uterine tissue into left abdominal …