Mahéra Al-Akoum

No ORCID on file · 8 papers in corpus · active 2006-2016

Study types

  • article 6
  • other 2

Condition tags

  • endometriosis 7
  • chronic_pelvic_pain 4
  • infertility 3
article 2016
Augmented Angiogenic Factors Expression via FP Signaling Pathways in Peritoneal Endometriosis
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jc.2016-1569

CONTEXT: is a potent angiogenic factor in endothelial cells. OBJECTIVE: We sought to determine whether or not the F-prostanoid receptor modulates angiogenesis in ectopic stromal cells. DESIGN: signaling was assessed. SETTING: The study was …

article 2014
Blood soluble interleukin 1 receptor accessory protein levels are consistently low throughout the menstrual cycle of women with endometriosis
Reproductive biology and endocrinology : RB&E ·doi:10.1186/1477-7827-12-51

BACKGROUND: A deficiency in the counter-regulatory mechanisms of interleukin 1 (IL1) may play a significant role in endometriosis pathogenesis and associated chronic inflammation. The aim of this study was to investigate peripheral blood le…

article 2011
Decreased concentrations of soluble interleukin-1 receptor accessory protein levels in the peritoneal fluid of women with endometriosis
Journal of reproductive immunology ·doi:10.1016/j.jri.2011.08.001
article 2011
Macrophage migration inhibitory factor stimulates the expression of matrix metalloproteinases 2 and 9 in endometriotic cells and up-regulates their activation level
·doi:10.1016/j.fertnstert.2011.07.521
other 2008
Abnormal interleukin 1 receptor types I and II gene expression in eutopic and ectopic endometrial tissues of women with endometriosis
Journal of reproductive immunology ·doi:10.1016/j.jri.2007.04.002

Interleukin-1 (IL1) is believed to play a central role in the immuno-inflammatory process associated with endometriosis. IL1 triggers cell activation via its receptor type I (IL1R1), but its receptor type II (IL1R2) is known instead as a sc…

other 2008
Imbalance in the peritoneal levels of interleukin 1 and its decoy inhibitory receptor type II in endometriosis women with infertility and pelvic pain
Fertility and sterility ·doi:10.1016/j.fertnstert.2007.06.019

OBJECTIVE: To evaluate the levels of interleukin-1beta (IL1beta) and its inhibitory soluble interleukin-1 receptor type II (IL1R2) in the peritoneal fluid (PF) of normal women and patients with endometriosis suffering from pelvic pain and i…

article 2007
Increased expression of interleukin-1 receptor type 1 in active endometriotic lesions
Reproduction (Cambridge, England) ·doi:10.1530/rep.1.01121

Abstract The establishment and progression of ectopic endometrial implants are dependent upon their interaction with and responsiveness to the stimuli present in their new environment. According to our and other previous studies, immune cel…

article 2006
Macrophage migration inhibitory factor expression in the intrauterine endometrium of women with endometriosis varies with disease stage, infertility status, and pelvic pain
Fertility and sterility ·doi:10.1016/j.fertnstert.2005.10.073