Christine Bruse

No ORCID on file · 14 papers in corpus · active 1998-2013

Study types

  • article 13
  • other 1

Condition tags

  • endometriosis 13
  • dysmenorrhea 2
  • infertility 1
article 2013
Pertubation With Lignocaine as a New Treatment of Dysmenorrhea Due to Endometriosis
·doi:10.1097/01.ogx.0000429298.55211.ad

Dysmenorrhea and infertility are the primary symptoms of endometriosis. Lignocaine (lidocaine, xylocaine) is an anesthetic that stabilizes membranes by blocking the action potential. The drug is used topically to induce local and regional a…

article 2013
Quality of life in patients with endometriosis and the effect of pertubation with lidocaine – a randomized controlled trial
Acta obstetricia et gynecologica Scandinavica ·doi:10.1111/aogs.12257

OBJECTIVE: Pertubation with lidocaine has been shown to reduce pain (on a VAS-scale) in women with endometriosis. A clinical study was performed to evaluate the effect of lidocaine pertubations on quality of life. DESIGN: Double-blind, rand…

article 2012
Cost of illness in women with endometriosis
article 2012
Pertubation with lignocaine as a new treatment of dysmenorrhea due to endometriosis: a randomized controlled trial
Human Reproduction ·doi:10.1093/humrep/der434

BACKGROUND: Endometriosis is a chronic inflammatory disease of unknown aetiology that can cause severe dysmenorrhea. Lignocaine has anti-inflammatory properties and exerts effects on nerve endings and intra-peritoneal macrophages. The objec…

article 2012
PIH14 Cost of Illness in Women with Endometriosis
·doi:10.1016/j.jval.2012.08.1886
article 2005
Basal release of urokinase plasminogen activator, plasminogen activator inhibitor-1, and soluble plasminogen activator receptor from separated and cultured endometriotic and endometrial stromal and epithelial cells
Fertility and Sterility ·doi:10.1016/j.fertnstert.2004.09.033

ObjectiveTo investigate whether separated and cultured endometriotic and endometrial stromal and epithelial cells release urokinase plasminogen activator (uPA), plasminogen activator inhibitor-1 (PAI-1), and soluble plasminogen activator re…

article 2004
Increased proteolysis in endometriotic tissue and endometrium in women who develop endometriosis may facilitate invasion
·doi:10.1016/j.ics.2004.06.009
article 2004
In situ localization of mRNA for the fibrinolytic factors uPA, PAI-1 and uPAR in endometriotic and endometrial tissue
Molecular human reproduction ·doi:10.1093/molehr/gah033

Endometriotic tissue grows invasively. The plasminogen-activating system is suggested to participate in degradation of extracellular matrix (ECM) and modulation of cell adhesion and migration. We have previously demonstrated elevated levels…

other 2003
Impact of epidermal growth factor and transforming growth factor beta-1 on the release of fibrinolytic factors from cultured endometrial and ovarian endometriotic stromal cells
Gynecologic and obstetric investigation ·doi:10.1159/000068950

We have investigated whether there are any differences in the release of urokinase plasminogen activator (uPA) and its inhibitor (PAI-1) from cultured endometrial and endometriotic stromal cells, and whether the release is regulated by epid…

article 2002
Effects of hormones on uPA, PAI‐1 and suPAR from cultured endometrial and ovarian endometriotic stromal cells
Acta obstetricia et gynecologica Scandinavica ·doi:10.1034/j.1600-0412.2002.810503.x

PROBLEM: To investigate whether endometriotic stromal cells release the urokinase plasminogen activator, soluble urokinase plasminogen activator receptor and plasminogen activator inhibitor-1. If so, to establish if there are any difference…

article 2002
Effects of hormones on uPA, PAI-1 and suPAR from cultured endometrial and ovarian endometriotic stromal cells1
·doi:10.1080/j.1600-0412.2002.810503.x
article 2001
Interleukin 1β, interleukin-6, and tumor necrosis factor-α in endometriotic tissue and in endometrium
Fertility and Sterility ·doi:10.1016/s0015-0282(00)01752-0

ObjectiveTo compare the levels of IL-1beta, IL-6, and TNFalpha in endometriotic tissue and in endometrium from women with endometriosis and healthy controls.DesignOpen.SettingDepartment of Obstetrics and Gynecology at a university hospital.…

article 2000
Production of Interleukins 1β, 6 and 8 and Tumor Necrosis Factor Alpha in Separated and Cultured Endometrial and Endometriotic Stromal and Epithelial Cells
Gynecologic and obstetric investigation ·doi:10.1159/000010269

The production of IL-1beta, IL-6, IL-8 and TNF-alpha was studied in short-time culture of separated stromal and epithelial cells. The cytokine secretion into culture medium was analyzed using immunoassay to evaluate the cytokine protein lev…

article 1998
Fibrinolytic factors in endometriotic tissue, endometrium, peritoneal fluid, and plasma from women with endometriosis and in endometrium and peritoneal fluid from healthy women
Fertility and Sterility ·doi:10.1016/s0015-0282(98)00285-4

ObjectiveTo determine whether there is a difference in fibrinolytic compounds in endometriotic tissue, endometrium, peritoneal fluid (PF), and plasma from women with endometriosis and in endometrium and PF from healthy women.DesignProspecti…