Sekizawa A

No ORCID on file · 8 papers in corpus · active 2001-2021

Study types

  • article 4
  • other 2
  • review 1

Condition tags

  • endometriosis 6
2021
Reproduction & fertility ·doi:10.1530/raf-20-0030

PurposeFollowing reports of an increase in implantation and pregnancy continuation rates by a higher percentage of Lactobacillus in the intrauterine microbiota, it has received attention in infertility treatment. This study aimed to examine…

article 2007
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists ·doi:10.1097/pgp.0b013e31802b41a8

To probe the mechanism of the development of ovarian cancer from endometriosis, which is a multistep process that involves the activation of oncogenes and inactivation of tumor suppressor genes, we evaluated p53 mutations in solitary endome…

other 2005
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists ·doi:10.1097/01.pgp.0000165173.90339.a2

Ovarian clear-cell carcinoma (OCCA) and ovarian endometrioid carcinoma (OEMC) are often associated with endometriosis. This study determined the immunohistochemical expression of steroid hormone receptors and cancer-related genes in OCCA an…

article 2004
Medical electron microscopy : official journal of the Clinical Electron Microscopy Society of Japan ·doi:10.1007/s00795-004-0252-5

Endometriosis shares some features characteristic of malignancy; however, it remains unclear whether endometriosis is a precursor to malignant disease. The objective is to determine the genetic relationship between endometriosis and ovarian…

article 2004
International Journal of Gynecology & Obstetrics ·doi:10.1016/j.ijgo.2004.04.036

OBJECTIVES: To clarify the role of specific genetic alterations in the multi-step process of malignant transformation of endometriosis. METHODS: In cases of ovarian endometrioid carcinoma, we separated regions of normal endometriosis, atypi…

review 2004
Medical electron microscopy : official journal of the Clinical Electron Microscopy Society of Japan ·doi:10.1007/s00795-003-0233-0

Endometriosis is considered to be a possible precancerous disease. Pathologically, we observed malignant transformation of endometriosis to clear cell carcinoma or endometriotic carcinoma of the ovary, via the step of atypical endometriosis…

article 2003
Gynecologic oncology ·doi:10.1016/s0090-8258(02)00149-x

ObjectiveAlthough ovarian clear cell adenocarcinoma (OCCA) and ovarian endometrioid adenocarcinoma (EC) are considered to be closely related to endometriosis, the mechanisms of carcinogenesis of these two malignancies and malignant transfor…

other 2001
Gynecologic oncology ·doi:10.1006/gyno.2001.6322

OBJECTIVE: Steroid sulfatase (STS) is an important enzyme that converts biological inactive steroid sulfate to active free steroid. As estrogen is thought to play an important role in cell proliferation in gynecological cancer, the existenc…