Osamu Yoshino

No ORCID on file · 90 papers in corpus · active 2002-2026

Study types

  • article 74
  • other 10
  • book-chapter 3
  • review 2

Condition tags

  • endometriosis 76
  • endometrioma 18
  • infertility 6
  • adenomyosis 5
  • dysmenorrhea 2
  • chronic_pelvic_pain 2
  • mesh:D004716 2
  • dyspareunia 1
  • bladder_endometriosis 1
article 2019
Journal of Obstetrics and Gynaecology Research ·doi:10.1111/jog.14157

AIM: The aim of this study was to investigate the efficacy of T2 star (T2*) mapping in diagnosing ovarian cysts/ tumors. METHODS: diameter circle, was set as much as possible inside ovarian tumors/cysts to measure T2*values, and mean T2* va…

article 2019
·doi:10.1055/a-0835-6119

Abstract Amenorrhea and osteoporosis are strongly associated in female athletes. Amenorrheic women show lower serum levels of brain-derived neurotrophic factor (BDNF) than eumenorrheic women. BDNF is known to regulate bone tissue developmen…

article 2019
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719119828112

ObjectsThere is growing evidence that sphingosine 1-phosphate (S1P) is involved in inflammatory diseases. As endometriosis is known as an inflammatory disease, we investigated the role of S1P system in the development of endometriosis.Metho…

article 2018
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719118806395

ObjectiveThe aim of this study was to clarify the expression of Ninj1 in endometriosis and adenomyosis lesions, and its inductive factor in human endometriotic stromal cells (ESCs).BackgroundNerve injury-induced protein 1 (Ninj1) is a molec…

article 2018
Journal of Obstetrics and Gynaecology Research ·doi:10.1111/jog.13702

Endometrioma is known to be an occurrence site of ovarian cancer, but there is no evidence on how to reduce the risk of canceration. Here, we report three cases of ovarian cancer arising from endometrioma during hormone therapies of GnRH an…

article 2017
European journal of pain (London, England) ·doi:10.1002/ejp.1133

BACKGROUND: Endometriosis is a gynaecological disease exhibiting severe pelvic pain, but the mechanism of pain production remains unknown. Bradykinin (BK) is known as an inflammatory mediator, and shows elevated levels in inflammatory disea…

article 2017
·doi:10.1016/j.jri.2017.10.025
article 2016
American journal of reproductive immunology (New York, N.Y. : 1989) ·doi:10.1111/aji.12592

OBJECTIVE: We investigated α-7 nAchR expression in human peritoneal macrophages and examined whether activation of nAchR might be a new therapy for endometriosis. MATERIALS AND METHODS: Human peritoneal fluid mononuclear cells (PFMC) were s…

article 2016
·doi:10.1016/j.jri.2016.04.073
article 2016
·doi:10.1016/j.jri.2016.04.241
article 2016
·doi:10.1111/jog.13226

AIM: Recent investigations have demonstrated that athletes with high relaxin-2 levels have a high risk of anterior cruciate ligament injuries, while athletes taking oral contraceptives (OC) have low relaxin-2 levels. It has not yet been cla…

article 2016

The aim of this study is to examine the regulation of follistatin, an activin-binding protein, in endometriosis. Endometrioma stromal cells (EoSCs) were obtained from 9 patients undergoing laparoscopy of the ovarian endometrioma. In culture…

article 2016
·doi:10.1016/j.jri.2016.10.054
article 2016
Journal of Obstetrics and Gynaecology Research ·doi:10.1111/jog.13056

AIM: The aim of this study was to investigate the prevalence of hypointensity on T2 star-weighted imaging (T2*WI), which is useful for detecting hemosiderin, in endometriomas and other ovarian tumors. The efficacy of detecting adhesions aro…

article 2015
·doi:10.1016/j.jri.2015.09.014
article 2014
American journal of reproductive immunology (New York, N.Y. : 1989) ·doi:10.1111/aji.12282

PROBLEM: Immune tolerance to endometriotic cells is important to promote endometriosis. Tryptophan 2,3-dioxygenase (TDO) enhances immune tolerance by catabolizing tryptophan to kynurenine. We studied whether interleukin-1β (IL-1β), a typica…

book-chapter 2014
·doi:10.1007/978-4-431-54421-0_27
article 2013
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jc.2012-3475

CONTEXT: Endometriosis is a chronic inflammatory disease in which immune response and production of estrogen in endometriotic tissues are involved in the development of the disease. Prostaglandin E2 (PGE2) stimulates aromatase (P450arom) ex…

article 2013
book-chapter 2012
·doi:10.1007/978-94-007-4234-5_17
article 2012
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719112463253

The aim of this study is to examine the regulation of follistatin, an activin-binding protein, in endometriosis. Endometrioma stromal cells (EoSCs) were obtained from 9 patients undergoing laparoscopy of the ovarian endometrioma. In culture…

article 2012
Fertility and sterility ·doi:10.1016/j.fertnstert.2012.07.1117

ObjectiveTo investigate a new role of interleukin (IL)-17A in endometriosis.DesignLaboratory study.SettingUniversity hospital.Patient(s)Patients with ovarian endometrioma undergoing laparoscopy or laparotomy.Intervention(s)Primary culture o…

article 2012
Human Reproduction ·doi:10.1093/humrep/des291

STUDY QUESTION: Is thymic stromal lymphopoietin (TSLP) involved in the pathophysiology of endometriosis? SUMMARY ANSWER: TSLP is up-regulated by interleukin (IL)-1β and may be involved in the development of endometriosis. WHAT IS KNOWN ALRE…

review 2012
Frontiers in bioscience (Scholar edition) ·doi:10.2741/s326

Proteinase-activated receptors (PARs) are G protein-coupled receptors activated by various proteinases. PARs play important roles in haemostasis, thrombosis, and inflammation. PAR1 and PAR2 are expressed in endometrial cells from the eutopi…

article 2012
Frontiers in bioscience (Elite edition) ·doi:10.2741/e416

Proteinase-activated receptors (PARs) are G protein-coupled receptors activated by various proteinases. PARs play important roles in haemostasis, thrombosis, and inflammation. PAR₁ and PAR₂ are expressed in endometrial cells from the eutopi…