Л.М. Михалева

Among all endometriosis lesions of female reproductive organs, ovarian endometrioma is the most discussed nosology. Since 2014, ovarian endometrioid cysts have been classified as benign tumors (WHO Classification of Tumours of Female Reprod…

ЦЕЛЬ ИССЛЕДОВАНИЯ Оценка иммуногистохимических параметров эндометрия у пациенток с гиперплазией эндометрия без атипии и аномальным маточным кровотечением (АМК) как предикторов эффективности гормональной терапии. МАТЕРИАЛ И МЕТОДЫ Обследован…

Benign ovarian tumors (BOT) have a significant impact on fertility and are associated with infertility, which, in turn, relates to endometrial receptivity and depends on the ovarian status, forming the so-called endometriopathy. Objective. …

Endometrial polyp (EP) is a frequent incidental finding during hysteroscopy in asymptomatic patients. To date, the pathogenesis of EPs has not been fully disclosed, which challenges the primary and secondary prevention of EPs and their targ…

Endometrial polyp (EP) is a frequent incidental finding during hysteroscopy in asymptomatic patients. To date, the pathogenesis of EPs has not been fully disclosed, which challenges the primary and secondary prevention of EPs and their targ…

Over the years, it has been discussed that adenomyosis is not merely endometriosis of the uterus, but an independent disease with its inherent pathogenesis and clinical mechanisms. Adenomyosis and endometriosis are distinguished not only by…

OBJECTIVE: To review the mechanisms of endometriosis development, including those related to epigenetic mutations, cellular dysregulation, inflammatory processes, and oxidative stress. METHODS: A systematic literature review regarding curr…

Endometriosis causes infertility and the alterations in endometrial receptivity. Pinopodia in eutopic endometrial epithelium may have significant implications in the endometriosis-associated infertility. The aim of this study is to ascertai…

Study Objective: To study impaired expression of estrogen (ER) and progesteron (PR) receptor isoforms during the implantation window in eutopic endometrium of infertile women associated with endometriosis genitalis externa (EGE). Study Desi…

Introduction. Endometriosis is an endless source of scientific investigations, but still the mechanisms of malignant transformation of ovarian endometriosis remain to be understood. Patients and methods. This study was conducted on surgical…

Study Objective: To expand the idea of the pathogenesis of implantation incompetence of endometrium in women with endometriosis-associated infertility. Study Design: open perspective comparative study. Materials and Methods. The study enrol…

Numerous studies on animal models endow prolactin with multiple functions, both physiological (reproduction, lactation, growth, metabolism, transport and electrolyte behaviour) and pathological (immunity and carcinogenesis). Prolactin is an…

The article highlights modern ideas about the role of the endometrium in the genesis of reproductive failures. A crucial place of chronic endometritis in the structure of the endometrial infertility factor in endometriosis is noted. Given t…

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This review focuses on pathogenesis of endometriosis, its possible biomarkers and role in endometriosis-associated ovarian cancer. We analyzed various databases to obtain new insights, theories, and biomarkers associated with endometriosis.…

ВВЕДЕНИЕ На сегодняшний день бесплодие отмечено почти у 10% пар репродуктивного возраста во всем мире. В настоящей статье рассмотрена одна из причин возникновения бесплодия, обусловленного эндометриозом яичников, — морфофункциональная непол…

This review summarizes current understanding of the pathogenesis of one of the most common forms of external genital endometriosis ovarian endometriomas. Due to their frequent occurrence in young women of reproductive age and extremely nega…

This article discusses the causes and mechanisms of the occurrence of infertility in endometriosis within the framework of versions and contraversions. The magnitude of the described problem is noted not only from a medical, but also from a…

The aim of the study was to analyze the effect of surgical intervention on the status of the ovarian follicular apparatus in patients with benign ovarian cystic tumors (BCOTs) based on the results of morphometric studies. Material and metho…

Glandular cystic ovarian endometriosis (OE) is characterized by a more intensive blood supply than cystic OE. This type of OE is characterized by a high proliferative glandular epithelial activity detected by an immunohistochemical study us…