On markers of early detection of endometriosis-associated ovarian tumours

In: Voprosy ginekologii, akušerstva i perinatologii · 2019 · vol. 18(4) , pp. 133–137 · doi:10.20953/1726-1678-2019-4-133-137 · W2987997905
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This paper analyzes literature and presents a view on ovarian endometriosis morphology, biomarkers, and genome, discussing its potential transformation into associated tumors, supported by molecular-genetic research.

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This article reviews medical literature and presents the authors’ perspective on the morphology, biomarkers, and genome of ovarian endometriosis, framing ovarian endometriosis as a distinct nosology with risk of transformation into atypical forms and endometriosis-associated ovarian tumours. It draws on molecular and genetic research to support the thesis that identifiable markers could enable earlier detection of such tumour progression. The authors’ main limitation is that this work is based on literature analysis rather than new experimental or clinical data. This paper is centrally about endometriosis — specifically ovarian endometriosis and markers for early detection of endometriosis-associated ovarian tumours.

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Gynecology, Obstetrics and Perinatology - Gynecology, Obstetrics and Perinatology - 2019 volume 18 issue 4 On markers of early detection of endometriosis-associated ovarian tumours Authors / Institutions Aleksandr I. Davydov / Lyudmila V. Mikhaleva / Оlga I. Patsap / The article analysizes data of medical literature and presents the authors’ point of view on the morphology, biomarkers, genome of ovarian endometriosis. The thesis is discussed according to which endometriosis of the ovaries is a specific individual nosology, which is characterised by the risks of transformation into atypical forms with the development of endometriosisassociated tumours. This is demonstrated by molecular and genetic research. Therefore, treatment of patients with ovarian endometriosis should not be confined to medication or passive observation only. Key words: atypical endometriosis, ovarian endometriosis, endometriosis-associated tumours. For citation: Davydov A.I., Mikhaleva L.M., Patsap О.I. On markers of early detection of endometriosis-associated ovarian tumours. Vopr. ginekol. akus. perinatol. (Gynecology, Obstetrics and Perinatology). 2019; 18(4): 133–137. (In Russian). DOI: 10.20953/1726-1678-2019-4-133-137 endometriosis should not be confined to medication or passive observation only. Key words: atypical endometriosis, ovarian endometriosis, endometriosis-associated tumours. For citation: Davydov A.I., Mikhaleva L.M., Patsap О.I. On markers of early detection of endometriosis-associated ovarian tumours. Vopr. ginekol. akus. perinatol. (Gynecology, Obstetrics and Perinatology). 2019; 18(4): 133–137. (In Russian). DOI: 10.20953/1726-1678-2019-4-133-137

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