Thomas D’Hooghe

No ORCID on file · 255 papers in corpus · active 1991-2026

Study types

  • article 181
  • review 35
  • letter 11
  • book-chapter 8
  • other 6

Condition tags

  • endometriosis 229
  • infertility 37
  • dysmenorrhea 9
  • chronic_pelvic_pain 8
  • dyspareunia 6
  • adenomyosis 3
  • endometrioma 2
  • die_deep_infiltrating 2
  • disambig:endometritis 1
  • bowel_endometriosis 1
article 2012
Human Reproduction ·doi:10.1093/humrep/des127

BACKGROUND: An early semi-invasive diagnosis of endometriosis has the potential to allow early treatment and minimize disease progression but no such test is available at present. Our aim was to perform a combined mRNA microarray and proteo…

article 2012
Human Reproduction ·doi:10.1093/humrep/des234

BACKGROUND: At present, the only way to conclusively diagnose endometriosis is laparoscopic inspection, preferably with histological confirmation. This contributes to the delay in the diagnosis of endometriosis which is 6-11 years. So far n…

article 2012
Human Reproduction ·doi:10.1093/humrep/des124

BACKGROUND: Paired-box 2 (Pax2) is involved in the development of the female genital tract and has been associated with endometrial pathologies. The expression of Pax2 is induced by epidermal growth factor (EGF) and estrogens. In the presen…

article 2012
Obstetrics and gynecology ·doi:10.1097/aog.0b013e31823fda8d

OBJECTIVE: To test the hypothesis that differential surface-enhanced laser desorption/ionization time-of-flight mass spectrometry protein or peptide expression in plasma can be used in infertile women with or without pelvic pain to predict …

article 2012
article 2012
·doi:10.1093/humrep/27.s2.45
article 2012
Human Reproduction ·doi:10.1093/humrep/des073

BACKGROUND: This study aimed to calculate costs and health-related quality of life of women with endometriosis-associated symptoms treated in referral centres. METHODS: A prospective, multi-centre, questionnaire-based survey measured costs …

article 2012
·doi:10.1016/j.fertnstert.2012.07.791
article 2012
Human Reproduction ·doi:10.1093/humrep/des299

STUDY QUESTION: How patient-centered are two included specialized endometriosis clinics relative to each other and how can they improve the patient-centeredness of their care? SUMMARY ANSWER: The validated ENDOCARE questionnaire (ECQ) relia…

article 2011
Reproductive biology and endocrinology : RB&E ·doi:10.1186/1477-7827-9-113

BACKGROUND: Endometriosis is associated with chronic subclinical inflammation. C-reactive protein (CRP), a marker of inflammation, could serve as a biomarker of endometriosis. We tested the hypothesis that a high sensitivity CRP assay (hsCR…

article 2011
Human Reproduction ·doi:10.1093/humrep/der231

BACKGROUND: Laparoscopic segmental bowel resection and reanastomosis for endometriosis with colorectal wall invasion can be associated with high complication rates. This study was performed to test the hypothesis that this high complication…

other 2011
·doi:10.1002/9781444398519.ch3

This chapter provides an economic perspective on the diagnosis and treatment of endometriosis. Endometriosis imposes a substantial economic burden on society. This burden originates from the time delay between onset of symptoms and diagnosi…

other 2011
·doi:10.1002/9781444398519.ch48

Although retrograde menstruation occurs in 76–90% of women, only 8–10% are known to develop endometriosis, which probably suggests that other factors might be involved in determining the susceptibility to endometriosis. The prevailing evide…

erratum 2011
Reproductive biology and endocrinology : RB&E ·doi:10.1186/1477-7827-9-44
article 2011
article 2011
Fertility and sterility ·doi:10.1016/j.fertnstert.2011.06.034

This study indicates that the immunobiology of macroscopically normal peritoneum is relevant to understand the pathogenesis of endometriosis. Peritoneal interleukin 6, interleukin 12, and ferritin were differentially expressed in women with…

article 2011
Fertility and sterility ·doi:10.1016/j.fertnstert.2011.05.090

ObjectiveTo assess the impact of endometriosis on health-related quality of life (HRQoL) and work productivity.DesignMulticenter cross-sectional study with prospective recruitment.SettingSixteen clinical centers in ten countries.Patient(s)A…

article 2011
article 2011
·doi:10.2143/tvg.67.23.2001087

Het belang van reproductieve chirurgie neemt af door de alomtegenwoordige beschikbaarheid van technieken van medisch begeleide voortplanting (MBV), maar een solide epidemiologisch bewijs voor deze evolutie ontbreekt. Om deze reden verrichtt…

article 2011
Human Reproduction ·doi:10.1093/humrep/der072

BACKGROUND: Multidisciplinary laparoscopic treatment is the standard of care for radical treatment of deep infiltrating pelvic endometriosis. If bowel resection is necessary, a muscle-split or Pfannenstiel incision is also required. The avo…

article 2011
Human Reproduction ·doi:10.1093/humrep/der215

BACKGROUND: This study aims to quantify the non-health-care costs of endometriosis in a sample of Belgian patients over a 30-month period. METHODS: A longitudinal study enrolled patients who underwent surgical treatment for endometriosis in…

article 2011
article 2011
Human Reproduction ·doi:10.1093/humrep/der169

BACKGROUND: Endometriosis is a common benign gynaecological disease. Epidemiological studies have demonstrated associations between endometriosis and ovarian cancer. Recent genome-wide association studies of ovarian cancer have identified s…

article 2011

Introduction: Endometriosis (the presence of endometrial-like tissue outside the uterus) affects 10% of women of reproductive age and is associated with dysmenorrhoea, pain at ovulation, dyspareunia, abnormal bleeding, chronic pelvic pain, …

article 2011
·doi:10.1093/humrep/26.s1.80