Takashi Okai

No ORCID on file · 8 papers in corpus · active 2003-2007

Study types

  • article 6
  • other 1
  • review 1

Condition tags

  • endometriosis 7
article 2007
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists ·doi:10.1097/pgp.0b013e31802b41a8

To probe the mechanism of the development of ovarian cancer from endometriosis, which is a multistep process that involves the activation of oncogenes and inactivation of tumor suppressor genes, we evaluated p53 mutations in solitary endome…

other 2005
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists ·doi:10.1097/01.pgp.0000165173.90339.a2

Ovarian clear-cell carcinoma (OCCA) and ovarian endometrioid carcinoma (OEMC) are often associated with endometriosis. This study determined the immunohistochemical expression of steroid hormone receptors and cancer-related genes in OCCA an…

article 2005
Fertility and sterility ·doi:10.1016/j.fertnstert.2005.02.034
article 2004
Medical electron microscopy : official journal of the Clinical Electron Microscopy Society of Japan ·doi:10.1007/s00795-004-0252-5
article 2004
International Journal of Gynecology & Obstetrics ·doi:10.1016/j.ijgo.2004.04.036

OBJECTIVES: To clarify the role of specific genetic alterations in the multi-step process of malignant transformation of endometriosis. METHODS: In cases of ovarian endometrioid carcinoma, we separated regions of normal endometriosis, atypi…

review 2004
Medical electron microscopy : official journal of the Clinical Electron Microscopy Society of Japan ·doi:10.1007/s00795-003-0233-0

Endometriosis is considered to be a possible precancerous disease. Pathologically, we observed malignant transformation of endometriosis to clear cell carcinoma or endometriotic carcinoma of the ovary, via the step of atypical endometriosis…

article 2004
·doi:10.15369/sujms1989.16.47

Several genetic alterations have been associated with the malignant transformation from endometriosis to ovarian cancer. However, the role of each genetic alteration in this multi-step process of tumorigenesis has not been clarified. Region…

article 2003
Gynecologic oncology ·doi:10.1016/s0090-8258(02)00149-x