Okai T
No ORCID on file
· 11 papers in corpus
· active 2001-2007
Study types
- article 5
- other 2
- review 1
Condition tags
- endometriosis 7
Top journals
- International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists 2
- Medical electron microscopy : official journal of the Clinical Electron Microscopy Society of Japan 2
- Reproductive medicine and biology 2
- Gynecologic oncology 2
- International Journal of Gynecology & Obstetrics 1
Frequent coauthors
- Takashi Okai 8
- Sekizawa A 7
- Akihiko Sekizawa 7
- Saito H 6
- Hiroshi Saito 6
- Kushima M 4
- Nagatsuka M 4
- Iwasaki S 4
- Junko Otsuka 4
- Miki Kushima 4
2007
PurposeThe purpose of this study was to predict developmental competence of human oocytes during ICSI via analysis of connexin 43 (Cx43) in cumulus cells surrounding mature oocytes.Materials and methodsHuman cumulus cells were manually sepa…
article
2007
To probe the mechanism of the development of ovarian cancer from endometriosis, which is a multistep process that involves the activation of oncogenes and inactivation of tumor suppressor genes, we evaluated p53 mutations in solitary endome…
2006
Background: Steroid levels have been used as the predictive parameters for oocyte maturation and embryo development. In the present study, estradiol and progesterone concentrations in the follicular fluid and serum were evaluated in conven…
other
2005
Ovarian clear-cell carcinoma (OCCA) and ovarian endometrioid carcinoma (OEMC) are often associated with endometriosis. This study determined the immunohistochemical expression of steroid hormone receptors and cancer-related genes in OCCA an…
article
2005
ObjectiveTo investigate the localization and expression of steroid sulfatase (STS) in cumulus cells obtained from subjects with and without endometriosis.DesignCase-control study.SettingIn vitro fertilization program at the Showa University…
article
2004
Endometriosis shares some features characteristic of malignancy; however, it remains unclear whether endometriosis is a precursor to malignant disease. The objective is to determine the genetic relationship between endometriosis and ovarian…
article
2004
OBJECTIVES: To clarify the role of specific genetic alterations in the multi-step process of malignant transformation of endometriosis. METHODS: In cases of ovarian endometrioid carcinoma, we separated regions of normal endometriosis, atypi…
review
2004
Endometriosis is considered to be a possible precancerous disease. Pathologically, we observed malignant transformation of endometriosis to clear cell carcinoma or endometriotic carcinoma of the ovary, via the step of atypical endometriosis…
2003
Background: Several parameters of early embryo development are known as predictors of implantation success. Recently, zygote or embryo morphological assessments are thought to be a major method of selection in embryo transfer. We expected …
article
2003
ObjectiveAlthough ovarian clear cell adenocarcinoma (OCCA) and ovarian endometrioid adenocarcinoma (EC) are considered to be closely related to endometriosis, the mechanisms of carcinogenesis of these two malignancies and malignant transfor…
other
2001
OBJECTIVE: Steroid sulfatase (STS) is an important enzyme that converts biological inactive steroid sulfate to active free steroid. As estrogen is thought to play an important role in cell proliferation in gynecological cancer, the existenc…